Results 141 to 150 of about 1,072,209 (309)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Bayes empirical Bayes approach to unsupervised learning of parameters in pattern recognition

open access: yes, 2014
In the pattern classification problem, it is known that the Bayes decision rule, which separates k classes, gives a minimum probability of misclassification. In this study, all parameters in each class are unknown. A set of unidentified input patterns is
Li, T.F.
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Making resources work harder

open access: yes, 2010
Publishers, librarians, academics and students are likely to benefit from innovative work going on at the University of Huddersfield linking use of library resources with final degree result.
Pattern, David   +2 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Distinction making and pattern recognition in management

open access: yes
The ability to make new distinctions in management, and to diffuse these rapidly throughout a company into shared practices, will be a corporate strategic advantage in the future.
Roos, Johan
core  

Pattern making for new fabric joining technologies [PDF]

open access: yes, 2018
Fabric joining methods of welding and bonding can bring new possibilities to garment design and construction, offering a number of benefits over traditional sewing. Current applications are mostly limited to sports apparel, performance wear and lingerie,
Etheridge, Elena
core  

GRAPHIC VARIANT FOR THE PATTERN OF SURFACES ENGENDERING - GRAPHIC PATTERN - MAKING OF SURFACES ENGENDERING IN WINDING, ASSOCIATED TO ROLLING AXOIDS -

open access: yesJournal of Industrial Design and Engineering Graphics, 2007
In this paper is proposed a graphic variant for the pattern of surfaces engendering in the process of winding.
BAICU Ioan, ABRUDAN Ovidiu
doaj  

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