Results 241 to 250 of about 1,072,209 (309)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

High-frequency ultrasound combined with superb microvascular imaging for differential diagnosis of basal cell carcinoma and seborrheic keratosis: a retrospective analysis with nomogram implementation. [PDF]

Front Med (Lausanne)
Chen G, Leng X, Liu W, Liao X, Li Y, Meng J, Cao Y.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Forecasting Nasdaq stock exchange time series using an improved recurrent spiking Pi-Sigma artificial neural network. [PDF]

Sci Rep
Egrioglu E, Bas E, Albayrak G.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

When health systems invest matters: temporal imbalance and the case for life-course reorientation. [PDF]

J Glob Health
Tian J, Tang L.
europepmc   +1 more source

Unveiling Arrhythmogenic Cardiomyopathy Masquerading as Myocarditis in a Professional Athlete. [PDF]

JACC Case Rep
Garba DL, Burka S, Bavishi A, Barouch LA, Martinez MW, Kanwal AS.   +5 more
europepmc   +1 more source

The clinicoradiological and pathological-molecular characteristics associated with spread through air spaces in stage IA invasive lung adenocarcinoma. [PDF]

Insights Imaging
Xu F, Li X, Zhao WH, Huo JW, Luo TY, Li Q.   +5 more
europepmc   +1 more source

Selective Modulation of Evidence Accumulation by Hippocampal Theta Oscillations During Mnemonic Decision-Making. [PDF]

Hum Brain Mapp
Robins PL, Gilbert JR, Luber B, Mustafa N, Bharti E, Stout JD, Carver FW, Deng ZD.   +7 more
europepmc   +1 more source