Results 111 to 120 of about 319,166 (311)
Arboreal Identification Supported by Fuzzy Modeling for Trunk Texture Recognition
Due to the natural variability of the arboreal bark there are texture patterns in trunk images with values belonging to more than one species. Thus, the present study analyzed the usage of fuzzy modeling as an alternative to handle the uncertainty in the
Adriano Bressane +4 more
doaj +1 more source
Pattern-matching commands [PDF]
The paper investigates the following question: what happens if we try to embed the pattern-matching facilities of Snobol4 in a more conventional language? It shows that the facilities can be improved in some significant ways. However, the control structures that underlie pattern-matching operations are radically different from the usual ones, and this ...
openaire +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
AbstractImplementation of a rule-based transformation engine consists of several tasks with various abstraction levels. We present a new tool called mtom for the efficient implementation of rule-based transformations. This engine should help to bridge the gap between rewriting implementations and practical applications.
Moreau, Pierre-Etienne +2 more
openaire +2 more sources
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Clique descriptor of affine invariant regions for robust wide baseline image matching [PDF]
Assuming that the image distortion between corresponding regions of a stereo pair of images with wide baseline can be approximated as an affine transformation if the regions are reasonably small, recent image matching algorithms have focused on affine ...
Tjahjadi, Tardi, Shin, Dongjoe
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

