Results 101 to 110 of about 319,166 (311)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Graph Pattern Matching: From Intractable to Polynomial Time

, 2010
Graph pattern matching is typically defined in terms of sub-graph isomorphism, which makes it an np-complete problem. Moreover, it requires bijective functions, which are often too restrictive to characterize patterns in emerging applications. We propose
Li, Jianzhong, Tang, Nan, Ma, Shuai, Fan, Wenfei; id_orcid, Wu, Yunpeng, Wu, Yinghui   +5 more
core  

Internal pattern matching in small space and applications [PDF]

In this work, we consider pattern matching variants in small space, that is, in the read-only setting, where we want to bound the space usage on top of storing the strings. Our main contribution is a space-time trade-off for the Internal Pattern Matching
Bathie, G., Starikovskaya, T., Charalampopoulos, Panagiotis, Starikovskaya, Tatiana, Bathie, Gabriel   +4 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

A Comprehensive Review of Static Memory Analysis

IEEE Access
This review aims to evaluate and compare various static analysis tools across multiple programming languages for memory management. The tools and techniques under scrutiny include pattern matching, symbolic execution, CppCheck, SharpChecker, FindBugs ...
Temidayo Akinyemi, Enoch Solomon, Abraham Woubie, Kari Lippert   +3 more
doaj   +1 more source

Methods for Domain Specification of Verification-Oriented Process Ontology

Моделирование и анализ информационных систем, 2019
User-friendly formal specifications and verification of parallel and distributed systems from various subject fields, such as automatic control, telecommunications, business processes, are active research topics due to its practical significance. In this
Natalia O. Garanina, Igor S. Anureev, Olesya I. Borovikova, Vladimir E. Zyubin   +3 more
doaj   +1 more source

Diversified Top-k Graph Pattern Matching

, 2013
Graph pattern matching has been widely used in e.g., social data analysis. A number of matching algorithms have been developed that, given a graph pattern Q and a graph G, compute the set M(Q;G) of matches of Q in G.
Wang, Xin, Fan, Wenfei; id_orcid, Wu, Yinghui   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Matched Filter for Acoustic Emission Monitoring in Noisy Environments: Application to Wire Break Detection

Acoustics
Regular inspections of important civil infrastructures are mandatory to ensure structural safety and reliability. Until today, these inspections are primarily conducted manually, which has several deficiencies.
Alexander Lange, Ronghua Xu, Max Kaeding, Steffen Marx, Joern Ostermann   +4 more
doaj   +1 more source