Results 81 to 90 of about 1,233,843 (271)

Polymer Adsorption on Disordered Substrate

open access: yes, 1997
We analyze the recently proposed "pattern-matching" phase of a Gaussian random heteropolymer adsorbed on a disordered substrate [S. Srebnik, A.K. Chakraborty and E.I. Shakhnovich, Phys. Rev. Lett. 77, 3157 (1996)].
Dinko Cule   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Reconstruction in German relative clauses : in favor of the matching analysis [PDF]

open access: yes, 2008
In this paper I argue in favor of a Matching Analysis for German relative clauses. The Head Raising Analysis is shown to fail to account for parts of the reconstruction pattern in German, especially cases where only the external head is interpreted and ...
Salzmann, Martin
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A Comprehensive Review of Static Memory Analysis

open access: yesIEEE Access
This review aims to evaluate and compare various static analysis tools across multiple programming languages for memory management. The tools and techniques under scrutiny include pattern matching, symbolic execution, CppCheck, SharpChecker, FindBugs ...
Temidayo Akinyemi   +3 more
doaj   +1 more source

Methods for Domain Specification of Verification-Oriented Process Ontology

open access: yesМоделирование и анализ информационных систем, 2019
User-friendly formal specifications and verification of parallel and distributed systems from various subject fields, such as automatic control, telecommunications, business processes, are active research topics due to its practical significance. In this
Natalia O. Garanina   +3 more
doaj   +1 more source

Triaxial antenna Patent [PDF]

open access: yes, 1968
Pattern and impedance matching improvements in transversely polarized triaxial ...
Black, W. W.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Home - About - Disclaimer - Privacy