Results 211 to 220 of about 110,266 (316)

Identifying risk factors for Alzheimer's disease from multivariate longitudinal clinical data using temporal pattern mining. [PDF]

BMC Bioinformatics
Spooner A, Mohammadi G, Sachdev PS, Brodaty H, Sowmya A.   +4 more
europepmc   +1 more source

A multi-level hypoglycemia early alarm system based on sequence pattern mining. [PDF]

BMC Med Inform Decis Mak, 2021
Yu X, Ma N, Yang T, Zhang Y, Miao Q, Tao J, Li H, Li Y, Yang Y.   +8 more
europepmc   +1 more source

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Exploring Human Mobility: A Time-Informed Approach to Pattern Mining and Sequence Similarity. [PDF]

Int J Geogr Inf Sci
Yang H, Angela Yao X, Whalen CC, Kiwanuka N.   +3 more
europepmc   +1 more source

Connections between Various Disorders: Combination Pattern Mining Using Apriori Algorithm Based on Diagnosis Information from Electronic Medical Records. [PDF]

Biomed Res Int, 2022
Ma H, Ding J, Liu M, Liu Y.
europepmc   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Potential of accelerometers to remotely early detect bovine ephemeral fever in cattle using pattern mining. [PDF]

Transl Anim Sci
Trieu LL, Bailey DW, Cao H, Son TC, Macor J, Trotter MG, O'Connor L, Tobin CT.   +7 more
europepmc   +1 more source

Supervised sequential pattern mining of event sequences in sport to identify important patterns of play: An application to rugby union. [PDF]

PLoS One, 2021
Bunker R, Fujii K, Hanada H, Takeuchi I.
europepmc   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

MiLoPYP: self-supervised molecular pattern mining and particle localization in situ. [PDF]

Nat Methods
Huang Q, Zhou Y, Bartesaghi A.
europepmc   +1 more source