Results 51 to 60 of about 2,599,171 (311)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Distances Between Formal Concept Analysis Structures [PDF]

Transactions on Graph Data and Knowledge
In this paper, we study the notion of distance between the most important structures of formal concept analysis: formal contexts, concept lattices, and implication bases.
Bazin, Alexandre, Kahn, Giacomo
doaj   +1 more source

Resilient Pattern Mining

2025 IEEE International Conference on Data Mining (ICDM)
35 pages, 13 ...
Pengxin Bian, Panagiotis Charalampopoulos, Lorraine A. K. Ayad, Manal Mohamed 0001, Solon P. Pissis, Grigorios Loukides   +5 more
openaire   +4 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Closed High Utility Pattern Mining over Data Stream Based on Projection in the Window

Taiyuan Ligong Daxue xuebao, 2022
A fast and effective algorithm EFIM_Closed_DS was proposed to mine closed and high utility itemsets in the data stream environment. The algorithm is based on the projection technology in the window, and the database projection technology and transaction ...
Muhang LI, Meng HAN, Zhiqiang CHEN, Hongxin WU, Xilong ZHANG   +4 more
doaj   +1 more source

THE IMPLEMENTATION OF HESITANT FUZZY SPATIAL CO-LOCATION PATTERN MINING ALGORITHM BASED ON PYTHON [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2020
As one of the important research directions in the spatial data mining, spatial co-location pattern mining aimed at finding the spatial features whose the instances are frequent co-locate in neighbouring domain.
Z. W. Liu, Z. W. Liu, B. Wei, B. Wei, C. L. Kang, C. L. Kang, J. W. Jiang, J. W. Jiang   +7 more
doaj   +1 more source

Mining Patterns That Respond to Actions [PDF]

Fifth IEEE International Conference on Data Mining (ICDM'05), 2006
Data mining focuses on patterns that summarize the data. In this paper, we focus on mining patterns that could change the state by responding to opportunities of actions.
Yuelong Jiang, Ke Wang 0001, Alexander Tuzhilin, Ada Wai-Chee Fu   +3 more
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Frequent Pattern mining with closeness Considerations: Current State of the art [PDF]

, 2011
Due to rising importance in frequent pattern mining in the field of data mining research, tremendous progress has been observed in fields ranging from frequent itemset mining in transaction databases to numerous research frontiers. An elaborative note on
Dr. J.L. Rana, Anurag Choubey
core  

Generalized Net of the Process of Sequential Pattern Mining by Generalized Sequential Pattern Algorithm (GSP)

, 2014
In the present paper is constructed a Generalized net model of a process of sequential pattern mining by a generalized sequential pattern algorithm. Sequence pattern mining is a technique used for predictive data mining.
Bureva, V., Evdokia Sotirova, Veselina Bureva, Panagiotis Chountas, Sotirova, E., Chountas, P.   +5 more
core   +1 more source