Results 41 to 50 of about 83,565 (264)

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Investigation into diagnostic agreement using automated computer-assisted histopathology pattern recognition image analysis

Journal of Pathology Informatics, 2012
The extent to which histopathology pattern recognition image analysis (PRIA) agrees with microscopic assessment has not been established. Thus, a commercial PRIA platform was evaluated in two applications using whole-slide images.
Joshua D Webster, Aleksandra M Michalowski, Jennifer E Dwyer, Kara N Corps, Bih-Rong Wei, Tarja Juopperi, Shelley B Hoover, R Mark Simpson   +7 more
doaj   +1 more source

Application of Supervised Machine Learning to Recognize Competent Level and Mixed Antinuclear Antibody Patterns Based on ICAP International Consensus

Diagnostics, 2021
Background: Antinuclear antibody pattern recognition is vital for autoimmune disease diagnosis but labor-intensive for manual interpretation. To develop an automated pattern recognition system, we established machine learning models based on the ...
Yi-Da Wu, Ruey-Kai Sheu, Chih-Wei Chung, Yen-Ching Wu, Chiao-Chi Ou, Chien-Wen Hsiao, Huang-Chen Chang, Ying-Chieh Huang, Yi-Ming Chen, Win-Tsung Lo, Lun-Chi Chen, Chien-Chung Huang, Tsu-Yi Hsieh, Wen-Nan Huang, Tsai-Hung Yen, Yun-Wen Chen, Chia-Yu Chen, Yi-Hsing Chen   +17 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Narrative Methodology to Recognize Iris Patterns By Extracting Features Using Gabor Filters and Wavelets

MATEC Web of Conferences, 2016
Iris pattern Recognition is an automated method of biometric identification that uses mathematical pattern-Recognition techniques on images of one or both of the irises of an individual’s eyes, whose complex random patterns are unique, stable, and can be
Shristi Jha, Sindhu B.M., Venkatesan S.
doaj   +1 more source

Fingerprint Recognition Using Gabor Filter with Neural Network [PDF]

Engineering and Technology Journal, 2014
The automated classification and matching of fingerprint images has been a challenging problem in pattern recognition over the past decades. This paper proposes a method to detect the rotation region based on Estimate Global Region (EGR) that has the ...
Ekbal H.Ali, Hussam A.A.Ali, Hanady a.Jaber   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Optimization of Curvilinear Tracing Applied to Solar Physics and Biophysics

Entropy, 2013
We developed an automated pattern recognition code that is particularly well suited to extract one-dimensional curvilinear features from two-dimensional digital images.
Markus J. Aschwanden, Eugene A. Katrukha, Bart De Pontieu   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Iris Patterns As A Biometric Tool For Forensic Identifications: A Review

Brazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2016
Human biometric features are considered unique, permanent, measureable and objective traits used as authentic tools for identification of an individual.
Jagmahender Singh Sehrawat, Deeksha Sankhyan   +1 more
doaj