Results 51 to 60 of about 430,392 (288)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Automated Quantitative Description of Spiral Galaxy Arm-Segment Structure [PDF]

open access: yes, 2013
We describe a system for the automatic quantification of structure in spiral galaxies. This enables translation of sky survey images into data needed to help address fundamental astrophysical questions such as the origin of spiral structure---a ...
Davis, Darren, Hayes, Wayne
core  

Optimization of Curvilinear Tracing Applied to Solar Physics and Biophysics

open access: yesEntropy, 2013
We developed an automated pattern recognition code that is particularly well suited to extract one-dimensional curvilinear features from two-dimensional digital images.
Markus J. Aschwanden   +2 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Vision-Based Sensor for Early Detection of Periodical Defects in Web Materials

open access: yesSensors, 2012
During the production of web materials such as plastic, textiles or metal, where there are rolls involved in the production process, periodically generated defects may occur.
Julio Molleda   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A Colour Code Algorithm For Signature Recognition

open access: yesELCVIA Electronic Letters on Computer Vision and Image Analysis, 2007
The paper "A Colour Code Algorithm for Signature Recognition" accounts an image processing application where any user can verify signature instantly. The system deals with a Colour code algorithm, which is used to recognize the signature. The paper deals
Vinayak B. Kulkarni
doaj   +1 more source

INFORMATION TECHNOLOGY OF AUTOMATIC DETECTION AND IDENTIFICATION OF STATIONARY OBJECTS WITH UNMANNED AERIAL VEHICLES

open access: yesСучасні інформаційні системи, 2020
The subject matter of the article is the process of developing information technology for the automated detection and identification of stationary objects by unmanned aerial vehicles arises.
Andrii Bеrеzhnyi   +2 more
doaj   +1 more source

Statistical uncertainty quantification to augment clinical decision support: a first implementation in sleep medicine

open access: yesnpj Digital Medicine, 2021
Machine learning has the potential to change the practice of medicine, particularly in areas that require pattern recognition (e.g. radiology). Although automated classification is unlikely to be perfect, few modern machine learning tools have the ...
Dae Y. Kang   +4 more
doaj   +1 more source

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