Results 51 to 60 of about 3,985,830 (299)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Iris Patterns As A Biometric Tool For Forensic Identifications: A Review
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2016 Human biometric features are considered unique, permanent, measureable and objective traits used as authentic tools for identification of an individual.
Jagmahender Singh Sehrawat +1 more
doaj
Vision-Based Sensor for Early Detection of Periodical Defects in Web Materials
Sensors, 2012 During the production of web materials such as plastic, textiles or metal, where there are rolls involved in the production process, periodically generated defects may occur.
Julio Molleda +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
New Area Based Metrics for Automatic Gait Recognition
, 2001 Gait is a new biometric aimed to recognise a subject by the manner in which they walk. Gait has several advantages over other biometrics, most notably that it is non-invasive and perceivable at a distance when other biometrics are obscured.
Foster, Jeff P. +5 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Automated recognition of design patterns for framework understanding.
RITA, 1997 System design is one of the most important tasks in the software development cycles but it is also one of the most complex and time-consuming tasks. Thus, reuse of existing designs becomes very important. Object-oriented frameworks are generic designs for specific application domains that enable the reuse of designs and domain expert experience.
Campo, Marcelo Ricardo +1 more
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Systems and Soft ComputingThis study introduces a multimodal intelligent diagnosis system for assessing teaching quality in higher education, integrating natural language processing (NLP) of classroom discourse with temporal sequence modeling for teaching behavior pattern ...
Jianguo Shi, Sulong Cai
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source