Results 51 to 60 of about 87,229 (314)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Iris Patterns As A Biometric Tool For Forensic Identifications: A Review

open access: yesBrazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2016
Human biometric features are considered unique, permanent, measureable and objective traits used as authentic tools for identification of an individual.
Jagmahender Singh Sehrawat   +1 more
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Computer vision on magnetic resonance images

open access: yes, 1988
Menhardt W, Schmidt K-H. Computer vision on magnetic resonance images. Pattern Recognition Letters. 1988;8(2):73-85.We present an approach for the automated interpretation of transaxial cranial magnetic resonance images.
Schmidt, Karl-Heinrich, Menhardt, Wido
core   +1 more source

Optimization of Curvilinear Tracing Applied to Solar Physics and Biophysics

open access: yesEntropy, 2013
We developed an automated pattern recognition code that is particularly well suited to extract one-dimensional curvilinear features from two-dimensional digital images.
Markus J. Aschwanden   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The development of automated palmprint identification using major flexion creases [PDF]

open access: yes, 2012
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyPalmar flexion crease matching is a method for verifying or establishing identity.
Cook, Thomas
core  

Automated recognition of 3D CAD model objects in laser scans and calculation of as-built dimensions for dimensional compliance control in construction

open access: yes, 2010
The construction industry lacks solutions for accurately, comprehensively and efficiently tracking the three-dimensional (3D) status of buildings under construction.
Bosché, Frédéric, Frédéric Bosché
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Vision-Based Sensor for Early Detection of Periodical Defects in Web Materials

open access: yesSensors, 2012
During the production of web materials such as plastic, textiles or metal, where there are rolls involved in the production process, periodically generated defects may occur.
Julio Molleda   +3 more
doaj   +1 more source

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