Results 131 to 140 of about 6,425,859 (282)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Anniversary of the Standard Club, 1886 - 1913

, 1913
A program for an anniversary event held by the Standard Club in 1913, featuring music, speeches, and a tribute to Mrs.
Standard Club of Dallas
core  

Pharmacokinetic parameters (mean ± standard deviation).

, 2016
Pharmacokinetic parameters (mean ± standard deviation).
Paul Hagedoorn (429178), Anne H. de Boer (445758), Onno W. Akkerman (2557939), Henderik W. Frijlink (429179), Huib A. M. Kerstjens (204289), Marcel Hoppentocht (2557942), Jan-Willem C. Alffenaar (2557945), Tjip S. van der Werf (102009)   +7 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Long term outcomes of angle, filtering, and combined angle and filtering surgery for primary congenital glaucoma

JFO Open Ophthalmology
Purpose: To report on long term follow-up of surgical results in primary congenital glaucoma (PCG). Study design: Retrospective chart review. Methods: The charts of all children presenting with and operated on for PCG in Alexandria Main University ...
Nader Bayoumi, Mahmoud Morsy, Mohamed Fouad, Eman Nabil Elsayed   +3 more
doaj   +1 more source

Minutes of the Standard Club, 1922-1923

, 1922
This volume contains the minutes of the Standard Club women's organization of Dallas, Texas from October 1922 through April 1923.
Standard Club of Dallas
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Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

[Minutes of the Standard Club, 1886, 1887, 1888, 1889]

, 1886
This volume contains the minutes of the meetings of the Standard Club women's organization of Dallas, Texas from 1886 through 1889. Also included are newspaper clippings, programs, and ephemera related to the Standard Club from the 1920s and 1930s.
Standard Club of Dallas
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source