Results 101 to 110 of about 5,167,279 (311)
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Chemise and bloomers combination, 1920
Pattern No. 4710: Combination chemise and bloomers with a curved gore set in at the crotch, elasticized leg openings, shoulder straps of ribbon, and a neckline trimmed with a ribbon bow. Bloomers can be made separately if desired. Additional information
Vogue Pattern Service
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Pattern No. 4778: Shirtwaist with a square neck and kimona-style sleeves that are "darted to the elbow at the lower edge and fastened with buttons." Embroidered material is set-in at the forearm and along the armhole of the shirtwaist.
Vogue Pattern Service
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Pattern No. 4806: Skirt is "laid in a plait from the lower edge of the pockets to the lower edge of the skirt." Pockets are fastened with a button. Skirt is "plain across the front" and gathered in the back. Pattern No.
Vogue Pattern Service
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Three-piece costume with draped skirt and long blouse, 1920
Pattern No. 4791: Collared coat with revers, a crushed girdle, and sleeves "finished at the lower edge with a wide turn-back cuff." Front of coat is laid in two plaits at either side, and coat is trimmed with buttons.
Vogue Pattern Service
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Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Pattern No. 4591: Two-piece hobble skirt opens to the left and is trimmed at the lower edge with buttons. Pattern No. 4595: Two-piece hobble skirt opens to the left and is trimmed with stitching.
Vogue Pattern Service
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