Results 151 to 160 of about 2,773,097 (263)

Time-series transcriptome of Brachypodium distachyon during bacterial flagellin-induced pattern-triggered immunity. [PDF]

Front Plant Sci, 2022
Ogasahara T, Kouzai Y, Watanabe M, Takahashi A, Takahagi K, Kim JS, Matsui H, Yamamoto M, Toyoda K, Ichinose Y, Mochida K, Noutoshi Y.   +11 more
europepmc   +1 more source

Oligogalacturonides (OGs) – triggered Immunity in Arabidopsis thaliana

Plants, unlike mammals, lack mobile defender cells and a somatic adaptive immune system, instead relying on the innate immunity of each cell and on systemic signals emanating from infection sites.
Laura Guerrisi, Giulia De Lorenzo, Chiara Degli Esposti, Daniela Pontiggia   +3 more
core  

A peptide-receptor module links cell wall integrity sensing to pattern-triggered immunity

Plants employ cell-surface receptors to perceive non- or altered-self, including the integrity of their cell wall. Here we identify a specific ligand–receptor module responsive to cell wall damage that potentiates immunity in Arabidopsis.
Zipfel, Cyril, Rhodes, Jack, Zhai, Keran
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Loss of function of MusaPUB genes in banana can provide enhanced resistance to bacterial wilt disease

Communications Biology
Plants deploy a sophisticated defense mechanism against pathogens through pattern recognition receptors (PRRs) and resistance (R) proteins, activating pattern-triggered immunity (PTI) and effector-triggered immunity (ETI). E3 ubiquitin ligases, notably U-
Leena Tripathi, Valentine Otang Ntui, Samwel Muiruri, Trushar Shah, Jaindra Nath Tripathi   +4 more
doaj   +1 more source

RING-Type E3 Ubiquitin Ligases AtRDUF1 and AtRDUF2 Positively Regulate the Expression of PR1 Gene and Pattern-Triggered Immunity. [PDF]

Int J Mol Sci, 2022
Yi SY, Lee M, Kwon SY, Kim WT, Lim YP, Kang SY.   +5 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

In planta transcriptomics reveals conflicts between pattern-triggered immunity and the AlgU sigma factor regulon. [PDF]

PLoS One, 2022
Wang H, Smith A, Lovelace A, Kvitko BH.
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

New alleles of Arabidopsis BIK1 reinforce its predominant role in pattern-triggered immunity and caution interpretations of other reported functions

The receptor-like cytoplasmic kinase BIK1 and its close homologue PBL1 have been widely recognized as central components of plant immunity. However, most genetic studies of BIK1 and PBL1 functions were carried out with single transfer DNA (T-DNA ...
Choi, Sera, DeFalco, Thomas A., Kim, Sung-Il, Wang, Hongze, Zhou, Jian-Min, Li, Meng, Fliegmann, Judith, Zipfel, Cyril; https://orcid.org/, Kong, Liang, Li, Xiuming, He, Ping, Nürnberger, Thorsten, Hu, Meijuan, Shan, Libo, Gao, Yong, Song, Beibei, Zhao, Yan, Ma, Shengwei   +17 more
core   +1 more source