Results 101 to 110 of about 10,567,002 (282)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Computers & Mathematics with Applications, 1986 AbstractThe primary aim of this paper is to describe the main principles of crystallographic patterns (CPs) and their distribution and connection with natural phenomena and subjects of applied art. It is shown that these principles are in many respects similar to those governing the behavior of two-dimensional crystals.One may already find in ancient ...
openaire +1 more source
“Digits: for Good”; How Patterns Can Help
Patterns, 2020 Sahar Farajnia, Sarah Callaghan
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Ada Lovelace Day and Celebrating Women in STEM
Patterns, 2020 Sarah Callaghan +2 more
doaj +1 more source
Pulsar scintillation patterns and strangelets
, 2013 We propose that interstellar extreme scattering events, usually observed as pulsar scintillations, may be caused by a coherent agent rather than the usually assumed turbulence of $\rm H_2$ clouds.
Pen, Ue-Li +2 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Revisitation Patterns and Disorientation [PDF]
, 2003 The non-linear structure of web sites may cause users to become disorientated. In this paper we describe the results of a pilot study to find measures of user revisitation patterns that help in predicting ...
Herder, E.
core +3 more sources