Results 31 to 40 of about 7,817 (262)

Intelligent pavement condition survey: Overview of current researches and practices

Journal of Road Engineering
Automated pavement condition survey is of critical importance to road network management. There are three primary tasks involved in pavement condition surveys, namely data collection, data processing and condition evaluation. Artificial intelligence (AI)
Allen A. Zhang, Jing Shang, Baoxian Li, Bing Hui, Hongren Gong, Lin Li, You Zhan, Changfa Ai, Haoran Niu, Xu Chu, Zilong Nie, Zishuo Dong, Anzheng He, Hang Zhang, Dingfeng Wang, Yi Peng, Yifan Wei, Huixuan Cheng   +17 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Sampietrini Stone Pavements: Distress Analysis Using Pavement Condition Index Method [PDF]

Applied Sciences, 2017
In several Italian cities, it is possible to find historical pavements such as the Sampietrini pavements, which are mainly located in the center of the city of Rome. The Sampietrini pavement is a particular road surface paved in natural stone with irregular sharp elements that are assembled by hand with the evident not plan effect.
ZOCCALI, PABLO, LOPRENCIPE, Giuseppe, Galoni, Andrea   +2 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Condition Survey for Evaluation of Pavement Condition Index of a Highway [PDF]

Civil Engineering Journal, 2019
Pavements are major means of highway infrastructure. Maintenance and rehabilitation of these pavements for the required serviceability is a routine problem faced by highway engineers and organizations. Improvement in road management system results in reduction of time and cost, the pavement condition survey plays a big role in the pavement management ...
Muhammad Saleem Zafar, Syed Naveed Raza Shah, Muhammad Jaffar Memon, Touqeer Ali Rind, Muhammad Afzal Soomro   +4 more
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Investigation of automobile roads pavement deterioration trends in Lithuania

Journal of Civil Engineering and Management, 2003
Currently there are three pavement management systems (PMS) used in Lithuania for planning and management of road maintenance and repair activities: HDM-III, HDM-4 and DAVASEMA (Lithuanian PMS).
Aivaras Braga, Virgaudas Puodziukas, Donatas ÄŒygas, Alfredas Laurinavičius   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source