Results 41 to 50 of about 53,706 (297)

Bumpy Roads Ahead: America's Roughest Rides and Strategies to Make our Roads Smoother [PDF]

open access: yes, 2013
These days, potholes and pavement deterioration make it a challenge to keep the wheel steady on America's roads and highways. More than a quarter of the nation's major urban roadways -- highways and major streets that are the main routes for commuters ...

core  

Bridge expansion joint in road transition curve: effects assessment on heavy vehicles [PDF]

open access: yes, 2017
Properly-designed road surfaces provide a durable surface on which traffic can pass smoothly and safely. In fact, the main causes that determine the structural decay of the pavement and its parts are the traffic loads.
Bonin   +10 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Public Perceptions of the Midwest’s Pavements - Iowa - Phase III [PDF]

open access: yes, 2001
There are several objectives to this report. The first objective is to describe the sample with regard to the physical pavement data and three measures of driver satisfaction.
Giese, James K.   +4 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Application of Soft Computing for Estimation of Pavement Condition Indicators and Predictive Modeling

open access: yesFrontiers in Built Environment, 2022
The pavement management system is recognized as an assertive discipline that works on pavement indices to predict the pavement performance condition. This study used soft computing methods such as genetic algorithms and artificial intelligence to propose
Shadi Hanandeh   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Public Perceptions of the Midwest’s Pavements - Wisconsin - Executive Summary [PDF]

open access: yes, 2001
This report summarizes Wisconsin results of a five year, Pooled Fund study involving the Wisconsin, Iowa, and Minnesota DOTs designed to 1) assess the public\u27s perceptions of the departments’ pavement improvement strategies and 2) to develop customer ...
Giese, James K.   +4 more
core   +4 more sources

The Road Pavement Condition Index (PCI) Evaluation and Maintenance: A Case Study of Yemen

open access: yesOrganization, Technology and Management in Construction: An International Journal, 2017
The pavement condition index (PCI) is a simple, convenient and inexpensive way to monitor the condition of the surface of roads, identify maintenance and rehabilitation (M-and-R) needs as well as ensure that road maintenance budgets are spent wisely.
Karim Fareed M.A.   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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