ANALYSIS OF ROAD DAMAGE DUE TO OVER LOADING (CASE STUDY: DEMAK -TRENGGULI ARTERIAL ROAD, CENTRAL JAVA PROVINCE, INDONESIA) [PDF]
The ability of a pavement structure in carrying out its function reduces in line with the increase of traffic load, especially if there are overloaded heavy vehicle passing through the road.
Abobaker Ali Langer, Ibrahim
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Rigid pavements distresses - pavement condition index evaluation [PDF]
Pavements require maintenance in order to provide good service levels during their life period. Because of the significant costs of this operation and the importance of a proper planning, a pavement evaluation methodology, named Pavement Condition Index (
Pereira, Tiago David da Costa Prudente
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Penaksiran Kerusakan Jalan Dengan Metode Pavement Condition Index Berbasis Spasial
Sarana dan prasarana transportasi memainkan peranan penting terhadap pertumbuhan sebuah wilayah. Jalan menjadi nfrastruktur yang akan menjamin konektivitas antar wilayah tetap terjadi, sehingga kualitas jalan akan menjamin kelancaran pergerakan moda ...
Rizal Hafel +2 more
doaj +1 more source
Avaliação de uma base de dados para um sistema de gerência de pavimentos para a província de Maputo-Moçambique [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.Um Sistema de Gerência de Pavimentos pode ser definido como sendo um sistema atividades interconectadas que envolve a ...
Retagi, Rui Mauro Teixeira
core
Utilization of Pavement Condition Index on Runway Pavement Sultan Babullah Ternate Airport
The Pavement Condition Index (PCI) assessment is one method used to assess the state of airport runway pavement. The runway (flexible pavement) of Sultan Babullah Ternate Airport, which has a size of 2300 m by 45 m, served as the site for PCI research in this study.
null Sabaruddin +2 more
openaire +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source

