Results 121 to 130 of about 18,351 (301)

Constitutive modelling and systematic evaluation of asphalt concrete’s viscoelastic tension-compression asymmetry effect on pavement performance [PDF]

Title on author's file: Constitutive modeling and systematic evaluation of asphalt concrete’s viscoelastic tension-compression asymmetry effect on pavement performance202407 bcchAccepted ManuscriptRGCPublishedGreen ...
Tan, Zhifei,, Li, Hui,, Leng, Z, Tan, Z, Jelagin, D, Li, H, Yin, B, Du, C, Du, Cong,, Yin, Binbin,, Cao, Peng,, Cao, P, Elaguine, Denis,, Leng, Zhen,   +13 more
core   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

Advanced Healthcare Materials, EarlyView.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao, Akhila Naru, Dhanush Gandavadi, Mengxi Zheng, Saraswathi Lanka, Hyeongjun Cho, Chau Nguyen Minh Hoang, Jianqiang Zhang, Ying Fang, Xing Wang   +9 more
wiley   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Accelerated Testing and Instrumentation: A Canadian Case Study [PDF]

, 2015
The primary objective of this paper is to describe how the CPATT Test Track is used to advance Canadian pavement engineering practices through the investigation of the impact of axle loads and environment on flexible and rigid pavement structures.
Tighe, Susan L.
core  

Research on asphalt pavement structure with cement treated large size macadam (CTB-50) base course.

PLoS ONE
Cement-treated large-size macadam base (CTB-50) has a high modulus, high strength, and good durability, which can increase the paving and rolling thickness, reduce the base layers, and enhance the overall structure of the pavement structure.
Bentao Zhou, Yuan Yao, Xiaoke Geng, Yingjun Jiang, Tiezheng Guan, Ji Liang, Yue Wang   +6 more
doaj   +1 more source

Advancing Concrete Pavement Rehabilitation and Strategic Management Through Nondestructive Testing at Toll Stations

Applied Sciences
In contrast to maintaining asphalt pavements, maintaining healthy and functional concrete pavements is a much greater challenge due to the especially brittle nature of concrete, which may require a more complex rehabilitation plan.
Konstantinos Gkyrtis, Christina Plati, Andreas Loizos   +2 more
doaj   +1 more source

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou, Zongjie Hu, Xiuwen Li, Huaman Geng, Yang Liu, Yajie Wang, Yunshu Yang, Guangdong Zhou, Yujie Hua, Di Wang   +9 more
wiley   +1 more source

Flexible pavement rehabilitation using pulverization. [PDF]

Pulverization is a roadway rehabilitation strategy that involves in-place recycling of the entire existing flexible pavement layer and some of the existing granular base layer (Figure 1).
California. Dept. of Transportation. Office of Pavement Engineering
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