Results 151 to 160 of about 2,193 (172)
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Su1166 Pax9 is Critical for Esophageal Epithelial Development
Gastroenterology, 2012Background and Aims: Autophagy is a normal physiological mechanism for the degradation of cellular proteins and organelles. Excessive autophagy induced by cellular stress leads to cell death. However, the exact role of autophagy in cancer is not completely clear. Beclin1 plays a central role in the regulation of autophagy.
Hao Chen +4 more
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Paired box 9 (PAX9) is one of the best‐known transcription factors involved in the development of human dentition. Mutations in PAX9 gene could, therefore, seriously influence the number, position and morphology of the teeth in an affected individual. To date, over 50 mutations in the gene have been reported as associated with various types of dental ...
O. Bonczek, V.J. Balcar, O. Šerý
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The Function and Regulatory Network of Pax9 Gene in Palate Development
Journal of Dental Research, 2018Cleft palate, a common congenital deformity, can arise from disruptions in any stage of palatogenesis, including palatal shelf growth, elevation, adhesion, and fusion. Paired box gene 9 (Pax9) is recognized as a vital regulator of palatogenesis with great relevance to cleft palate in humans and mice.
R. Li, Z. Chen, Q. Yu, M. Weng, Z. Chen
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The dominant negative mutation of PAX9 in nonsyndromic tooth agenesis
Clinical Oral InvestigationsPaired box 9 (PAX9) is a transcription factor that plays a critical role in the development of human dentition. Although various mutations in the PAX9 gene have been identified to date, the mechanisms by which these mutations cause non-syndromic tooth agenesis (NSTA) remain not fully understood.
Yuhua, Pan +7 more
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Pax9 drives development of the upper jaw but not teeth in zebrafish
Developmental BiologyLoss of dentition has occurred repeatedly throughout vertebrate evolution. Cyprinid fish, including zebrafish, form teeth only deep within the pharynx, not on their oral jaws. However, zebrafish still robustly express transcription factors associated with mammalian tooth development in the neural crest-derived mesenchyme surrounding the mouth.
Sandhya Paudel +3 more
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PAX7, PAX9 and RYK Expression in Cleft Affected Tissue
Medicina (Lithuania), 2021Martins Vaivads +2 more
exaly
Function of Pax1 and Pax9 in the sclerotome of medaka fish
Genesis, 2008Akira Kudo, Keiji Inohaya
exaly
Pax9 and Gbx2 Interact in the Pharyngeal Endoderm to Control Cardiovascular Development
Journal of Cardiovascular Development and Disease, 2020Deborah Henderson +2 more
exaly