Results 271 to 280 of about 2,102,666 (322)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Prussian Blue Nanoparticles Promoting Diabetic Bone Regeneration via Mitochondrial Recovery. [PDF]

BME Front
Gu A, Lao A, Li W, Liu Z, Zhou C, Cai J, Chen Q, Lin K, Song L, Wu X, Liu J.   +10 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Patella Baja Incidence, Risk Factors and Motion After Revision Total Knee Arthroplasty. [PDF]

Arthroplast Today
Gapinski Z, Perry N, Courington R, Tabbaa A, Green C, Haidukewych G.   +5 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Neuroscience meets food choice: Implicit and explicit consumer responses to plant-based vs animal-based foods. [PDF]

Curr Res Food Sci
Inguscio BMS, Carcaterra G, Cherubino P, Rossi D, Madini G, Fraccascia L, Babiloni F, Cartocci G.   +7 more
europepmc   +1 more source

Nature-Inspired Redox Shuttle with Regenerable Antioxidant for Efficient All-Perovskite Tandem Solar Cells. [PDF]

Nanomicro Lett
Meng R, Du L, Li C, Wan Z, Shi J, Zhang Y, Liu W, Zhi C, Jia C, Tan L, Xiao C, Wang XZ, Song L, Gao X, Li Z.   +14 more
europepmc   +1 more source

Separate and combined effects of Gua⁺ and SCN^- ions on charge carrier dynamics in mixed Sn-Pb perovskites.

J Mater Chem A Mater
Nespoli J, van der Meer MJ, van der Poll LM, Liu X, Savenije TJ.   +4 more
europepmc   +1 more source

Spatial Variation in Cd, Pb, Hg, and Zn Accumulation in Edible Wild-Growing Mushroom Species from Different Environmentally Loaded Areas in Southern Poland: Risk Assessment and Implications for Consumer Safety. [PDF]

Toxics
Rusin M, Domagalska J, Czendlik A, Wróbel N, Kidoń A.   +4 more
europepmc   +1 more source

Spatiotemporal delivery of multifunctional nanozymes for neuroinflammation alleviation via autophagy modulation in spinal cord injury. [PDF]

Mater Today Bio
Jiang H, Jiang L, Xia T, Yu J, Bu Y, Shen H, Zhu L, Lin C, Wang Y, Chen Y, Liu R, Shi J, Wang J, Deng J, Liu H, Pan X.   +15 more
europepmc   +1 more source