Results 51 to 60 of about 1,678,662 (232)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Measurements of electrons from heavy-flavour hadron decays in pp, p-Pb and Pb-Pb collisions with ALICE at the LHC

open access: yes, 2014
Heavy-flavour hadrons, i. e. hadrons carrying charm or beauty quarks, are a well-suited probe to study the Quark-Gluon Plasma (QGP) in relativistic heavy-ion collisions.
Filho, E. Pereira de Oliveira
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Microbial Communities of the Providence River [PDF]

open access: yes, 2015
The Providence River has been industrialized for over one-hundred years. Industries such as oil storage and metal recycling facilities have left high levels of pollutant metals, including lead (Pb), in the soil and water.
Kratch, Jacqueline
core   +1 more source

ψ(2S) Suppression in Pb-Pb Collisions at the LHC

open access: yesPhysical review letters
Published by APS, College Park, Md.
Alocco, G   +209 more
openaire   +9 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Quarkonium production in ALICE at the LHC

open access: yes, 2014
In heavy-ion collisions at the LHC, the ALICE Collaboration is studying Quantum Chromodynamics (QCD) matter at very high energy density where the formation of a Quark Gluon Plasma (QGP) is expected.
Hadjidakis, Cynthia
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Low-Mass Dielectron Production in pp, p–Pb and Pb–Pb Collisions with ALICE [PDF]

open access: yesNuclear Physics A, 2015
4 pages, 8 figures, Proceedings of Quark Matter 2015 conference, September 27-October 3, 2015, Kobe ...
openaire   +5 more sources

K*(892)$^{0}$ and $\Phi$(1020) production in Pb-Pb collisions at $\sqrt{s_{\rm NN}}$ = 2.76 TeV

open access: yes, 2015
The yields of the K*(892)$^{0}$ and $\Phi$(1020) resonances are measured in Pb-Pb collisions at $\sqrt{s_{\rm NN}}$ = 2.76 TeV through their hadronic decays using the ALICE detector.
ALICE Collaboration
core   +1 more source

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