Results 31 to 40 of about 185,096 (262)

Costs of avoiding net negative emissions under a carbon budget

open access: yesEnvironmental Research Letters, 2021
The 2 °C and 1.5 °C temperature targets of the Paris Agreement can be interpreted as targets never to be exceeded, or as end-of-century targets. Recent literature proposes to move away from the latter, in favour of avoiding a temperature overshoot and ...
Kaj-Ivar van der Wijst   +2 more
doaj   +1 more source

Application of Peptides Containing the Cleavage Sequence of Pro-TNFα in Assessing TACE Activity of Whole Cells [PDF]

open access: yes, 2002
Tumor necrosis factor-α (TNFα) is presumably shed from cell membranes by TNFα-cleaving enzyme (TACE). The peptides SPLAQAVRSSSR and Dabcyl-LAQAVRSSSR-Edans, each encompassing the cleavage sequence of pro-TNFα recognized by TACE, were applied to intact ...
Becker, Bernhard F.   +3 more
core   +1 more source

Impact factors for quantifying country-level terrestrial biodiversity intactness footprints (IBIF)

open access: yesScientific Data
There is an increasing demand for consistent methods and tools to quantify biodiversity footprints: the magnitude of biodiversity loss associated with all direct and indirect impacts associated with a given human activity or economic actor.
Aafke M. Schipper   +7 more
doaj   +1 more source

Faculty Development Program in Dokuz Eylül School of Medicine: In the process of curriculum change from traditional to PBL [PDF]

open access: yes, 2002
Introduction: In Dokuz Eylül School of Medicine (DESM) a faculty development program is being carried out by the "Trainers' Training Committee". DESM made a fundamental change in its curriculum from traditional to Problem-based Learning (PBL) in 1997 ...
Abacioglu, Hakan   +5 more
core  

IL‐2 Free Expansion of T Cells with Immunofilaments

open access: yesAdvanced Healthcare Materials, EarlyView.
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck   +4 more
wiley   +1 more source

Problem based learning in mental health nursing : the students experience. [PDF]

open access: yes, 2012
Problem based learning (PBL) is well established within the field of health-care education for professionals worldwide, although little has been done to explore the experiences of students undertaking a PBL course in mental health nursing.
Barrow   +35 more
core   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

open access: yesAdvanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko   +16 more
wiley   +1 more source

Convective structure of the planetary boundary layer of the ocean during gale [PDF]

open access: yes, 1986
The structure of the Planetary Boundary Layer (PBL) was measured, using an airborne lidar, over the Atlantic Ocean during several intensive observation periods of the Genesis of Atlantic Lows Experiment (GALE). Primary emphasis is on the understanding of
Boers, R., Melfi, S. H.
core   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

open access: yesAdvanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar   +7 more
wiley   +1 more source

UPAYA MENINGKATKAN KEAKTIFAN BELAJAR PESERTA DIDIK KELAS VIIA DENGAN MODEL PROBLEM BASED LEARNING DI MTS MUHAMMADIYAH TRUCUK KLATEN TAHUN PELAJARAN 2021/2022

open access: yesJurnal PAJAR (Pendidikan dan Pengajaran), 2021
The purpose of this research was to increase students’ learning at grade VII A through Problem Based Learning (PBL) at MTS Muhammadiyah Trucuk Klaten in the academic year 2021/2022. The method in this study was classroom action research.
Sriwiyata
doaj   +1 more source

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