The Effects of CB2R Activation on Inflammatory Pathways in Dermatomyositis [PDF]
Background/Objectives: Dermatomyositis is an autoimmune disease with heterogeneous symptoms and many potential drivers. Nonpsychoactive cannabinoids have shown promise in treating some subtypes of DM; however, the reasons behind this were unclear.
Rohan Dhiman +8 more
doaj +2 more sources
Analysis of differential expression of microRNA, bta-miR-93 in lipopolysaccharide challenged peripheral blood mononuclear cells of cattle [PDF]
The present study was undertaken to analyse the differences in the microRNA (miRNA) expression in lipopolysaccharide (LPS) challenged and unchallenged peripheral blood mononuclear cells (PBMCs) of cattle.
A.B. Venu +6 more
doaj +1 more source
Perturbation of specific transcripts in peripheral blood mononuclear cells in breast cancer: A case- control pilot study [PDF]
Introduction: Breast cancer (BC) is the most common type of diagnosed cancer worldwide and the leading cause of cancer death in women and it is the second most frequent cancer-causing mortality for women worldwide.
Nadia PANERA +12 more
doaj +1 more source
A Comparative Study on the Efficiency of CRISPR-Cas9 in Human Embryonic Kidney 293 Cells and Peripheral Blood Mononuclear Cells for Disruption in Programmed Cell Death Protein 1 [PDF]
CRISPR-Cas9 is the most important tool in genome engineering in recent years. The efficiency of this instrument on active and non-active genes is variable.
Seyed Ali Alambeladi +2 more
doaj +1 more source
The effect of eight weeks high- intensity interval training alone and combined with resistance training on miR-33b expression in PBMCs of overweight/obese women [PDF]
Background: The expression of microRNAs as epigenetic regulators of lipid metabolism pathways disrupt in obese condition, in this regard miR-33b has particular importance.
Zhaleh Pashaei +2 more
doaj +1 more source
MiR-490-5p Functions as an OncomiR in Breast Cancer by Targeting NFATc4 [PDF]
Breast cancer is a serious health problem worldwide in women. MicroRNAs are small non-coding RNAs of 18–25 nucleotides in length that post-transcriptionally modulate gene expression. MiR-490 has been reported as a tumor suppressor and oncomiR microRNA in
Amir Hassan Nikfarjam, Mohsen gholami
doaj +1 more source
Small size excretory/secretory (ES) antigens of the Haemonchus contortus parasite have intense interest among researchers for understanding the molecular basis of helminths immune regulation in term of control strategies.
Muhammad Ehsan +9 more
doaj +1 more source
Clinical significance of LncRNA-MIAT as a non-invasive diagnostic marker of non-Hodgkin's lymphoma associated with occult hepatitis C virus infection [PDF]
Aims: the current research aimed to investigate LncRNA-MIAT in patients with non-Hodgkin lymphoma (NHL) and to assess its correlation with clinicopathological features and treatment protocols of NHLs among Egyptian patients with Occult hepatitis C virus (
Nearmeen Rashad +6 more
doaj +1 more source
Correlation between Expression of hsa-miR-490-5p and NFAT5 in Peripheral Blood Mononuclear Cell Obtained from Breast Cancer Patients [PDF]
Breast cancer is a complex genetic disease that has an average annual incidence of two million people and the second leading cause of death among women all over the world.
Amirhassan Nikfarjam +3 more
doaj +1 more source
Metabolic Syndrome Is Associated with Oxidative Stress and Proinflammatory State
Metabolic syndrome (MetS) is associated with increased risk of developing diabetes and cardiovascular diseases. MetS is also characterized by an increase of oxidative stress which contributes to impaired inflammation, vascular function, and ...
Margalida Monserrat-Mesquida +7 more
doaj +1 more source

