Results 61 to 70 of about 578,033 (291)

Comparison of correct classification rate (CCR) [%] of each of MSM [12], the proposed 2D-PCA MSM, the proposed 2D-PCA-R MSM (θ = −10), and the proposed B-2D-PCA-R MSM on CASIA-C [14] (slow walk fs).

, 2021
Comparison of correct classification rate (CCR) [%] of each of MSM [12], the proposed 2D-PCA MSM, the proposed 2D-PCA-R MSM (θ = −10), and the proposed B-2D-PCA-R MSM on CASIA-C [14] (slow walk fs).
Yumi Iwashita (11261748), Ryo Kurazume (9529108), Adrian Stoica (9297896), Hitoshi Sakano (11261751)   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Multivariate analysis of grain yield attributes and spot blotch incidence in wheat (Triticum aestivum L.) under sub-Himalayan agroclimatic condition

Electronic Journal of Plant Breeding
An Elite Spring Wheat Yield Trial (EWYT) was conducted with 50 diverse genotypes of Wheat (Triticum aestivum L.) and analyzed by multivariate analysis during 2018-19 rabi season. Correlation analysis revealed positive association of plant height, grains
Ponaganti Shiva Kishore1, Suvendu Kumar Roy1*, Saikat Das2, S. Vishnupriya1, Basid Ali1, Lakshmi Hijam1, Moumita Chakraborty1, Puspendu Dutta3, Rupsanatan Mandal4 and Sanghamitra Rout5
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Assessment of variation in rice maintainer lines using principal component analysis

Electronic Journal of Plant Breeding
The aim of this study was to explore the characteristics essential for a maintainer line to effectively complement the A lines in hybrid rice production.
B. Edukondalu1, V. Ram Reddy1, T. Shobha Rani1, CH. Aruna Kumari2 and B. Soundharya3
doaj   +1 more source

Analytical method development of pitavastatin-loaded SNEDDS formulation: Multivariate analysis regarding ultraviolet spectrophotometry analysis

Journal of Food and Pharmaceutical Sciences, 2019
Herein, this work aimed to develop and assess feasibility of multivariate model of partial least square analysis for specific quantification of pitavastatin (PVT)-loaded self-nano emulsion (SNE) formulation using UV Vis spectrophotometry. PVT loaded into
Kuncahyo I, Choiri S, Fudholi A, Abdul Rohman, Ronny Martien   +4 more
doaj   +1 more source

martaajarzyna/PCA-ForAnalysisOfBiodiversityChange: First release of PCA for biodiversity assessments (Jarzyna and Stagge)

, 2022
This is the code for using Principal Component Analysis (PCA) for assessments of change in multiple facets of biodiversity (manuscript in review by Jarzyna and Stagge)
Marta Jarzyna
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source