Results 191 to 200 of about 331,090 (323)

RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma

open access: yesAdvanced Science, EarlyView.
RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang   +6 more
wiley   +1 more source

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

open access: yesAdvanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen   +16 more
wiley   +1 more source

Associating serum testosterone levels with African ancestral prostate cancer health disparities. [PDF]

open access: yesSci Rep
Lebelo MT   +7 more
europepmc   +1 more source

Quantitative Evaluation of Passive Cutaneous Anaphylaxis (PCA) Using a Hand-Held Spectrophotometer.

open access: bronze, 1996
Hiroshi Akiyama   +6 more
openalex   +2 more sources

Room A, 10/17/2000 2: 00 PM - 4: 00 PM (PS) PCA with Tramadol Versus Morphine: Results of a Multicenter Study [PDF]

open access: bronze, 2000
Guido Schuepfer   +4 more
openalex   +1 more source

Orally Administered Functional Polyphenol‐Nanozyme‐Armored Probiotics for Enhanced Amelioration of Intestinal Inflammation and Microbiota Dysbiosis

open access: yesAdvanced Science, EarlyView.
This study presents a novel polyphenol‐nanozyme‐armored probiotic system (ECA@EcN) for enhanced treatment of inflammatory bowel disease (IBD). By integrating chitosan‐modified epigallocatechin gallate (EGCG‐CS) with gold nanozymes, the system effectively scavenges ROS, improves probiotic viability, and restores gut microbiota balance.
Yong Zhu   +12 more
wiley   +1 more source

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