Results 281 to 290 of about 527,772 (339)

Robust sparse smooth principal component analysis for face reconstruction and recognition. [PDF]

PLoS One
Wang J, Xie X, Zhang L, Li J, Cai H, Feng Y.   +5 more
europepmc   +1 more source

Hosts and Commensal Bacteria Synergistically Antagonize Opportunistic Pathogens at the Single‐Cell Resolution

Advanced Science, EarlyView.
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang, Ziguang Wang, Anqi Liu, Jinshu Li, Jingjing Zhuang, Xiaowen Ji, Paul I. Mulama, Maoye Li, Haiqun Cao, Eng‐King Tan, Wei Liu   +10 more
wiley   +1 more source

Prostate cancer screening in transgender patients Why current Canadian screening policies need to be better tailored to our patients. [PDF]

Can Urol Assoc J
Nguyen DD, Ahmad I, Al-Daqqaq Z, Rosella LC, Hird A, Wallis CJD, Grober ED, Lofters A, Kulkarni GS, Millman A, Krakowsky Y.   +10 more
europepmc   +1 more source

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma

Advanced Science, EarlyView.
This study utilizes patient‐derived osteosarcoma organoids and CRISPR screening to identify ERCC6 and HNRNPM as key mediators of cisplatin resistance via the PI3K/AKT pathway and BAX alternative splicing. These findings provide novel insights and potential therapeutic targets for overcoming chemoresistance in osteosarcoma.
Ruiling Xu, Sai Zhu, Wenchao Zhang, Haodong Xu, Chao Tu, Honghui Wang, Lu Wang, Na He, Tang Liu, Xiaoning Guo, Xiaolei Ren, Zhihong Li   +11 more
wiley   +1 more source

Digital spatial profiling identifies phospho-JNK as a biomarker for early risk stratification of aggressive prostate cancer. [PDF]

Front Oncol
Eickelschulte S, Kaczorowski A, Janke F, Riediger AL, Lazareva O, Böning S, Kristiansen G, Schwab C, Stenzinger A, Sültmann H, Duensing S, Duensing A, Görtz M.   +12 more
europepmc   +1 more source

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

IOL Power Calculation After Laser-Based Refractive Surgery: Measured vs. Predicted Posterior Corneal Astigmatism Using the Barrett True-K Formula. [PDF]

J Clin Med
De Rosa G, Criscuolo D, Longo L, Allegrini D, Romano MR.   +4 more
europepmc   +1 more source

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

ELOVL2 mediated stabilization of AR contributes to enzalutamide resistance in prostate cancer. [PDF]

Front Cell Dev Biol
Cen J, Guo J, Zeng X, Song X, Ge S, Chen M, Li Q, Yu Y, Lv D, Zhao S.   +9 more
europepmc   +1 more source