Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target. [PDF]
, 2018 Prostate cancer (PCa) is a leading cause of mortality and morbidity globally. While genomic alterations have been identified in PCa, in contrast to some other cancers, use of such information to personalize treatment is still in its infancy.
Dorff, Tanya +6 more
core +3 more sources
Upregulated wnt-11 and mir-21 expression trigger epithelial mesenchymal transition in aggressive prostate cancer cells [PDF]
, 2020 Prostate cancer (PCa) is the second-leading cause of cancer-related death among men. microRNAs have been identified as having potential roles in tumorigenesis.
Arisan, E.D. +15 more
core +1 more source
Toroidal PCA via density ridges [PDF]
Statistics and Computing, 33(5):107, 2023, 2022 Principal Component Analysis (PCA) is a well-known linear dimension-reduction technique designed for Euclidean data. In a wide spectrum of applied fields, however, it is common to observe multivariate circular data (also known as toroidal data), rendering spurious the use of PCA on it due to the periodicity of its support.
arxiv +1 more source
Reduksi Dimensi untuk Meningkatkan Kinerja Pengklasteran Perilaku Siswa pada Sistem e-Learning
Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2021 Pandemi corona telah mengubah proses pembelajaran dari yang semula tatap muka secara langsung (offline) menjadi pembelajaran secara daring (online).
Yuni Yamasari +4 more
doaj +1 more source
A Comparison of LUCC Detection Algorithms in a Mesoamerican Lowland Tropical Forest
Acta Universitatis Carolinae Geographica, 2021 Land use and land cover changes occur throughout the world, but none is more concerning than tropical deforestation, much of it for agricultural purposes. Rural-rural frontier migrant farmers such as those colonizing the Sierra del Lacandón National Park
Laurel Sutter, David López-Carr
doaj +1 more source
Domain swapping and amyloid fibril conformation [PDF]
, 2012 For several different proteins an apparent correlation has been observed between the propensity for dimerization by domain-swapping and the ability to aggregate into amyloid-like fibrils.
Van Der Wel, PCA
core +1 more source
Potential Partnerships: Progressive Criminology, Grassroots Organizations and Social Justice
International Journal for Crime, Justice and Social Democracy, 2015 Criminologists around the globe are writing about the disproportionate criminalization of minority groups and – in the US in particular – about racial disproportionality in all aspects of the criminal justice system.
Tim Goddard +2 more
doaj +1 more source
Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures. [PDF]
, 2020 Non-invasive assessment of the biological aggressiveness of prostate cancer (PCa) is needed for men with localized disease. Hyperpolarized (HP) 13C magnetic resonance (MR) spectroscopy is a powerful approach to image metabolism, specifically the ...
Ahamed, Fayyaz +12 more
core +1 more source
A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer. [PDF]
, 2015 Targeting specifically primary prostate cancer (PCa) cells for immune therapy, gene therapy or molecular imaging is of high importance. The PCA3 long non-coding RNA is a unique PCa biomarker and oncogene that has been widely studied.
Fradet, Yves +5 more
core +2 more sources
Smoke recognition based on the depth learning
Dianzi Jishu Yingyong, 2018 Based on the second generation Artificial Intelligence Learning System(TensorFlow), this paper constructs a neural network to detect smoke images, and uses an improved motion detection algorithm to intercept the image of suspected smoke area.
Wang Tao, Gong Ningsheng, Jiang Guixiang
doaj +1 more source