Results 171 to 180 of about 62,563 (288)

Native <i>Bacillus</i>-Based Probiotic Consortia Suppress <i>Vibrio parahaemolyticus</i> and Restructure Hatchery Water Microbiomes in Shrimp Larval Systems. [PDF]

Pathogens
Pazmiño-Gomez B, Rodas-Pazmiño K, Pazmiño-Pérez R, Tapia-Guijarro T, Balcazar-Quimi W, Valle-Asan S, Salazar-Vera S, Villalva-Vera M, Ochoa-Fajardo D, Rodas-Neira E.   +9 more
europepmc   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Porcine gut loops to explore the impact of amino acids on the host-microbiota crosstalk in the ileum. [PDF]

Front Microbiol
Renois F, Hervet C, Barc C, Kasal-Hoc N, Jones E, Roux C, Gagnon D, Chalvon-Demersay T, Beaumont M, Meurens F.   +9 more
europepmc   +1 more source

Disecting Banking Dea Efficiency [PDF]

, 2006
Callen, Yolanda Fuertes, Cinca, Carlos Serrano, Mar Molinero, Cecilio   +2 more
core  

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

The pollination syndrome of parasitic plants depends on the environment. [PDF]

Plant Cell Physiol
Tóth P, Huizinga S, Bouwmeester H.
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Protocol for metabolite extraction and sample preparation from primary astrocytes for mass spectrometry-based metabolomic analysis. [PDF]

STAR Protoc
Chang YG, Lin GM, Lin CY, Chern Y.
europepmc   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Transcriptomic dataset of the invasive species <i>Thunbergia alata</i> and its congener <i>Thunbergia grandiflora</i> (Acanthaceae) in Cali, Colombia. [PDF]

Data Brief
Ruiz-Londoño D, Pérez-Mesa PA, Suárez-Baron H.   +2 more
europepmc   +1 more source