Results 91 to 100 of about 240,855 (328)

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

open access: yesAdvanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

Supply- and demand-side developments influencing growth in the debit market [PDF]

open access: yes
On August 3, 2006, the Payment Cards Center of the Federal Reserve Bank of Philadelphia hosted a workshop led by Ronald Congemi, senior vice president of strategic industry relations for First Data Corporation, to examine developments on both the supply ...
Julia S. Cheney
core  

AI‐Driven Acceleration of Fluorescence Probe Discovery

open access: yesAdvanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang   +18 more
wiley   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

open access: yesAdvanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li   +11 more
wiley   +1 more source

A METÁFORA NO DISCURSO DO TRANSGRESSOR METAPHOR IN TRANSGRESSIVE DISCOURSE

open access: yesForma y Función, 2010
Resumo A metáfora se materializa nos discursos através de múltiplas regras específicas de aparecimento. Este trabalho tem como objetivo verificar quais são os mecanismos, através dos quais, a metáfora funciona no discurso transgressor.
Jefferson Barbosa de Souza   +1 more
doaj  

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

Diámetro mesiodistal de incisivos y caninos superiores e inferiores. Índices incisivos. Matanzas, 2012

open access: yesRevista Médica Electrónica, 2014
El tamaño de los dientes permite establecer un diagnóstico precoz de la falta de espacio para su ubicación futura en el arco dentario y practicar tratamientos interceptivos tempranos. El propósito de este trabajo fue determinar el diámetro mesiodistal de
Yanet de Armas González   +3 more
doaj  

rebeliões do PCC

open access: yesRevista de Antropologia da UFSCar, 2017
O Primeiro Comando da Capital (PCC), coletividade originada no interior das prisões paulistas no início da década de 1990, hoje está presente na grande maioria das prisões e zonas urbanas de São Paulo. Em 2006, uma megarrebelião envolvendo 84 prisões, acompanhada pelo que ficou conhecido como “os ataques do PCC”, sinalizou sua dimensão e ...
openaire   +2 more sources

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