Results 11 to 20 of about 5,268 (99)

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

Advanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang, Xingcan Pan, Yongling Ying, Ziqian Bai, Jingming Zhang, Zhuang Shao, Jialiang Qian, Hongwei Li, Ning Zhang, Fan Yang, Yuan Liu, Xing Yang   +11 more
wiley   +1 more source

Patient iPSC‐derived astrocytes reveal impaired homeostasis and reactive‐like features in propionic acidemia

The Journal of Pathology, EarlyView.
Abstract Propionic acidemia (PA) is a neurometabolic disorder caused by propionyl‐CoA carboxylase deficiency with frequent neurological involvement, yet cell‐type‐specific mechanisms remain poorly defined. We established human induced pluripotent stem cell (iPSC)‐derived astrocytes (iAs) from patients harboring PCCA or PCCB mutations and investigated ...
Irene González‐Garnacho, Mar Álvarez, Francisco Zafra, Pilar Rodríguez‐Pombo, Lourdes R Desviat, Eva Richard   +5 more
wiley   +1 more source

Nonwoven‐Based Textile Architectures for Energy Storage Applications: Materials, Preparation, Characterization, and Prospects

Advanced Materials Interfaces, Volume 13, Issue 16, 18 August 2026.
Nonwoven textile architectures are emerging as versatile platforms for next‐generation energy storage, demonstrating how tailored materials and fabrication strategies enhance ion transport, conductivity, flexibility, and scalability for high‐performance sustainable devices.
Tarikul Islam, Md. Hanif Munshi, Rijon Saha, Shaikh Almoon Hussain, Aqib Adnan Shafin, Shumsul Arefin, Md. Kamruzzaman   +6 more
wiley   +1 more source

Identification, reliability, and validity of drug–drug interaction checkers in chronic diseases: A systematic review

British Journal of Pharmacology, Volume 183, Issue 16, Page 4532-4561, August 2026.
Abstract Drug–drug interactions (DDIs) pose major risks in chronic disease management where polypharmacy is common. Although digital DDI tools are used widely to aid healthcare professionals, tools rely on theoretical interactions. This limitation questions their reliability and validity for clinical relevancy.
Brayden Ng Gibson, Sri Chodapuneedi, Huan Yee Koh, Sugandha Gupta, Danijela Gasevic, Anna Yuanyuan Wang, Catia Marzolini, Saye Khoo, Lorena Romero, Lachlan Dalli, Jack Janetzki, Harvey Jia Wei Koh, Stella Talic   +12 more
wiley   +1 more source

Brain Morphology in Subacute Spinal Cord Injury: Insights Into Functional Recovery Across Brain Networks

Brain and Behavior, Volume 16, Issue 7, July 2026.
ABSTRACT Background Spinal cord injury (SCI) induces widespread structural brain reorganization extending beyond primary sensorimotor areas, yet the extent to which brain morphometry across the whole brain can inform functional recovery alongside established clinical variables remains unclear. Methods We retrospectively analyzed 79 individuals with SCI
Lorenzo Diana, Jothini Sritharan, Nicola Brunello, Ernst Christiaanse, Rajeev K. Verma, Giuseppe A. Zito   +5 more
wiley   +1 more source

The Swiss Haemophilia Registry–Report From the First 8 Years

Haemophilia, Volume 32, Issue 4, Page 923-932, July/August 2026.
ABSTRACT Introduction Patient registries capture disease related information and provide a valuable source for real‐world data on rare diseases and their management. The Swiss Haemophilia Registry (SHR) was established in 2015 on the basis of a new Swiss federal human research act.
Alessandra Bosch, Lorenzo Alberio, Pierre Fontana, Lukas Graf, Johanna A. Kremer Hovinga, Nicolas von der Weid, Mattia Rizzi, Manuela Albisetti, the Swiss Haemophilia Network   +8 more
wiley   +1 more source

Structural Connectivity of Functionally Defined Episodic Memory Networks: A Large‐Scale Connectome–Behavior Study

Brain and Behavior, Volume 16, Issue 6, June 2026.
Abstract Background Previous task‐based fMRI work in a large cohort of young adults identified nine large‐scale functional brain networks whose encoding‐related responsivity was robustly associated with individual differences in episodic memory. It remains unclear whether structural connectivity within these task‐fMRI‐defined networks explains inter ...
Neda Ghasemi, David Coynel, Andreas Papassotiropoulos, Dominique J. F. de Quervain   +3 more
wiley   +1 more source

A RiboCancer cell line panel reveals that CLL‐associated Rps15 mutations translationally rewire transcription through codon‐specific tRNA accommodation defects

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Recurrent point mutations in ribosomal proteins (RPs) RPL10 and RPS15 are found in T‐cell acute lymphoblastic leukemia (T‐ALL) and chronic lymphocytic leukemia (CLL), respectively. Furthermore, deletions of RPL5, RPL11, and RPL22 are frequent in hematologic diseases such as Diamond Blackfan Anemia, T‐ALL, multiple myeloma, and in a variety of ...
Anaïs Astier, Marino Caruso, Stijn Vereecke, Paulo E. Santo, Coralie Capron, Carine Froment, Dana Rinaldi, David Cabrerizo Granados, Marine Leclercq, Jonathan Royaert, Jelle Verbeeck, Naomy Pasau, Laura Plassart, Daniele Pepe, Steven Verbruggen, Hermes Paraqindes, Simon Lebaron, Virginie Marcel, Sébastien Durand, Clément Chapat, Gerben Menschaert, Pierre Close, Francesca Rapino, Frédéric Catez, Julien Marcoux, Célia Plisson‐Chastang, Kim De Keersmaecker   +26 more
wiley   +1 more source

Traceable Traceless Delivery Tags

Helvetica Chimica Acta, Volume 109, Issue 6, June 2026.
ABSTRACT This study elaborates on traceless tags for the thiol‐mediated uptake (TMU) of amine‐containing substrates of interest (SOIs). Traceless tags typically contain linkers that can be enzymatically cleaved to trigger the release of SOIs in their native form.
Julia Moreno, Xudong Ren, Saidbakhrom Saidjalolov, Pierre Josso, Naomi Sakai, Stefan Matile   +5 more
wiley   +1 more source

An Integrative Review of Registered Nurses' Understandings of Organisational Culture and Cultures of Care in the Aged Care Sector

Journal of Advanced Nursing, Volume 82, Issue 5, Page 4800-4826, May 2026.
ABSTRACT Aim The aim of this integrative review was to explore registered nurses' understandings of organisational culture and cultures of care in aged care. Design Integrative literature review. Methods A literature search was conducted of Medline (OVID), CINAHL Plus with Full Text, Scopus, Proquest Nursing and Allied Health, and Informit databases in
Deborah Magee, Karen Francis, Holly Randell‐Moon, Samantha Jakimowicz, Marguerite Bramble   +4 more
wiley   +1 more source