Results 71 to 80 of about 369,505 (333)

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source

Left Ventricular Remodeling Risk Predicted by Two-Dimensional Speckle Tracking Echocardiography in Acute Myocardial Infarction Patients with Midrange or Preserved Ejection Fraction in Western Romania

Therapeutics and Clinical Risk Management, 2021
Diana Aurora Bordejevic,1 Tudor Pârvănescu,2 Lucian Petrescu,1 Cristian Mornoș,1 Ioan Olariu,1 Simina Crișan,1 Cristina Văcărescu,1 Mihai Lazăr,1 Vlad Ioan Morariu,2 Ioana Mihaela Citu,2 Mirela Cleopatra Tomescu,2 Dragoș Cozma1 1Cardiology ...
Bordejevic DA, Pârvănescu T, Petrescu L, Mornoș C, Olariu I, Crișan S, Văcărescu C, Lazăr M, Morariu VI, Citu IM, Tomescu MC, Cozma D   +11 more
doaj  

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

Advanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo, Zhiqing Zhao, Wei Wang, Jianfang Niu, Bing Wang, Yunfei Lin, Wei Guo, Taiqiang Yan   +7 more
wiley   +1 more source

Efficacy of Combined 5-Fluorouracil and Photodynamic Therapy in Glioma Spheroids

, 2018
Standard treatment regimens consisting of surgery, radiation and chemotherapy have proven ineffective for the treatment of high-grade gliomas such as glioblastoma multiforme (GBM).
Singh, Karanjit
core   +1 more source

A specified procedure for distress identification and assessment for urban road surfaces based on PCI [PDF]

, 2017
In this paper, a simplified procedure for the assessment of pavement structural integrity and the level of service for urban road surfaces is presented.
Loprencipe, Giuseppe, PANTUSO ROMERO, Antonio   +1 more
core   +2 more sources

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

Accuracy of Machine Learning Models for Early Prediction of Major Cardiovascular Events Post Myocardial Infarction: A Systematic Review and Meta-Analysis

Reviews in Cardiovascular Medicine
Background: Major adverse cardiovascular events (MACEs) significantly affect the prognosis of patients with myocardial infarction (MI).
Yi Xiang, Dong Liu, Leilei Guo, Yuhua Zheng, Xiaoman Xiong, Tao Xu   +5 more
doaj   +1 more source

Pompeo Colajanni e l’antifascismo in Sicilia. Un dialogo con Emanuele Macaluso

Diacronie. Studi di Storia Contemporanea, 2021
Emanuele Macaluso (1924-2021), a prominent exponent of the PCI, is interviewed by Carmelo Albanese on the figure of Pompeo Colajanni (1906-1987), one of the most important and well-known figures of the Italian Resistance.
Carmelo ALBANESE
doaj  

Gate‐Dielectric Surface Engineering With Fluorinated Monolayers: Minimizing Contact Resistance and Nonidealities in OFETs

Advanced Electronic Materials, EarlyView.
Surface engineering of gate dielectrics with fluorinated self–assembled monolayers significantly improves the performance of organic field–effect transistors. In this study, Al2O3 functionalized with fluorinated phosphonic acids reduces contact resistance and hysteresis while achieving near‐zero threshold voltages, offering an alternative to ...
Shaghayegh Mesforush, Alba Cazorla, Hayley Melville, Philippe Blanchard, Hagen Klauk, Ute Zschieschang, Min Zhang, Lamiaa Fijahi, Marta Mas‐Torrent, Esther Barrena   +9 more
wiley   +1 more source

A Review on Magnesium Based Metal Hydrides for Thermal Energy Storage Systems

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The hydrogen storage in metal hydrides is an imminent, innovative, and environmentally beneficial approach that offers benefits for example, an ample amount of storage and elasticity in terms of thermodynamics necessary for hydrogen absorption and release.
Asif Nizam, Prem Kumar Chaurasiya, Vinod Kumar Sharma, Ranjith Krishna Pai   +3 more
wiley   +1 more source