Results 71 to 80 of about 460,193 (379)

The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma [PDF]

open access: yes, 2008
We investigated the cytotoxicity and biology of the novel broad-spectrum hydroxamic acid-based histone deacetylase inhibitor (HDACi), PCI-24781. PCI-24781 was studied alone and combined with bortezomib in Hodgkin lymphoma (L428) and non-Hodgkin's ...
Andrew Evens   +9 more
core   +1 more source

Design and Implementation Aspects of a novel Java P2P Simulator with GUI

open access: yes, 2008
Peer-to-peer networks consist of thousands or millions of nodes that might join and leave arbitrarily. The evaluation of new protocols in real environments is many times practically impossible, especially at design and testing stages. The purpose of this
Chrissikopoulos, V.   +3 more
core   +1 more source

Parent-child interaction in Nigerian families: conversation analysis, context and culture [PDF]

open access: yes, 2008
This paper uses a conversation analysis (CA) approach to explore parent child interaction (PCI) within Nigerian families. We illustrate how speech and language therapists (SLTs), by using CA, can tailor recommendations according to the interactional ...
Annabel Burns   +15 more
core   +2 more sources

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

open access: yesArthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler   +8 more
wiley   +1 more source

FONDAPARINUX USAGE IN NON-ST-ELEVATION ACUTE CORONARY SYNDROME

open access: yesРоссийский кардиологический журнал, 2015
Anticoagulation treatment is a vital component of acute coronary syndrome treatment. Selection of the most efficient and safe drug for the acute coronary syndrome patients without ST elevation (NSTEACS) depends on the strategy of treatment and is in fact
G. V. Mardaryan, S. A. Abugov
doaj   +1 more source

Intervention en santé publique à un cas nouvellement diagnostiqué d’hépatite C associé à une lacune dans les pratiques de prévention et de contrôle des infections dans un établissement dentaire en Ontario, Canada

open access: yesCanada Communicable Disease Report, 2021
Contexte : La Circonscription sanitaire du district d’Haliburton, Kawartha, Pine Ridge a étudié une exposition dans un établissement dentaire opérationnel de l’Ontario à une infection par le virus de l’hépatite C (VHC) nouvellement diagnostiquée causée ...
Cassandra Johnston   +10 more
doaj   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro   +4 more
wiley   +1 more source

Phenotypic characterisation and production system of the Nordestino horse from a multivariate perspective

open access: yesScientific Reports
Zootechnical data is a big challenge in the extensive rearing system of Brazilian locally adapted breeds once smallholdings with limited resources and funds rear them. So, information on Brazil's breeding system of locally adapted breeds is still scarce;
Neila Lidiany Ribeiro   +6 more
doaj   +1 more source

Complete Revascularization of Stable STEMI Patients Offers a Significant Benefit if Done During the Index PCI, but Not if It’s Done as a Staged Procedure

open access: yesInternational Journal of General Medicine, 2021
Roberto C Cerrud-Rodriguez,1 Syed Muhammad Ibrahim Rashid,1 Karlo A Wiley,1 Maday Gonzalez,1 Valeriia A Kosmacheva,1 Isabella Castillero-Norato,2 Cornelia Rivera,1 Pedro Villablanca,3 Jose Wiley1 1Montefiore-Einstein Center for Heart and Vascular Care ...
Cerrud-Rodriguez RC   +8 more
doaj  

Clinical impact of FFR‐guided PCI compared to angio‐guided PCI from the France PCI registry

open access: yesCatheterization and Cardiovascular Interventions, 2021
AbstractObjectivesWe sought to compare, in a national French registry (FrancePCI), the clinical impact of fractional flow reserve (FFR)‐guided percutaneous coronary intervention (PCI) compared with angio‐guided PCI at 1 year.BackgroundFFR has become the invasive gold standard to quantify myocardial ischemia generated by a coronary stenosis in patients ...
Julien Adjedj   +9 more
openaire   +2 more sources

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