Results 81 to 90 of about 350,311 (304)

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

AGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang, Yuan Xue, Yeting Lou, Hao Han, Xiaohan Zhong, Zhou Liu, Tianxu Han, Meili Wang, Wenjian Jiang, Hongjia Zhang, Haiyang Li, Yuanfei Zhao   +11 more
wiley   +1 more source

The Clinical Outcomes of Primary Angioplasty in Hospitalized Patients with ST-Segment Elevation Acute Myocardial Infarction Were Investigated at Imam Reza Hospital from 1399 to 1401 [PDF]

Journal of Cardio-Thoracic Medicine
Introduction: Ischemic heart disease (IHD) is a major global health concern with significant implications for patient mortality and life expectancy. Effective management of IHD heavily relies on vascular reconstruction procedures, including percutaneous ...
Omid Khosravi, Mohammad Mahdi Shekarian Yazd   +1 more
doaj   +1 more source

Relationship Between Hospital Volume and Outcomes of Minimally Invasive Esophagectomy for Esophageal Cancer: Analysis of the National Clinical Database in Japan

Annals of Gastroenterological Surgery, EarlyView.
According to multivariable analysis conducted using a hierarchical logistic regression model, using VHH as the reference group, the odds ratios for mortality by hospital volume category were as follows: VLH, 2.70 (p < 0.0001); LH, 1.72 (p = 0.052); MH, 1.70 (p = 0.034); and HH, 1.43 (p = 0.173).
Soji Ozawa, Hiraku Kumamaru, Yuko Kitagawa, Kazuo Koyanagi, Junya Oguma, Harushi Udagawa, Hiroaki Miyata, Yasushi Toh, Hisahiro Matsubara   +8 more
wiley   +1 more source

Application of Machine Learning Algorithms in Predicting Major Adverse Cardiovascular Events after Percutaneous Coronary Intervention in Patients with New-Onset ST-Segment Elevation Myocardial Infarction

Reviews in Cardiovascular Medicine
Background: This study aimed to develop and validate a predictive model for major adverse cardiovascular events (MACE) following percutaneous coronary intervention (PCI) in patients with new-onset ST-segment elevation myocardial ...
Min Chen, Cuiling Sun, Li Yang, Ting Zhang, Jing Zhang, Chunli Chen   +5 more
doaj   +1 more source

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

Annals of Gastroenterological Surgery, EarlyView.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino, Ken‐ichi Okada, Yohei Masugi, Eisuke Iwasaki, Masaki Mori   +4 more
wiley   +1 more source

A New SVDD-Based Multivariate Non-parametric Process Capability Index

, 2018
Process capability index (PCI) is a commonly used statistic to measure ability of a process to operate within the given specifications or to produce products which meet the required quality specifications.
Chaudhuri, Arin, Kakde, Deovrat, Shaw, Diana   +2 more
core   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

Advanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Assessing Quality in Interventional Practice: Identifying Meaningful and Actionable Metrics

Reviews in Cardiovascular Medicine
Interventional cardiologists should insist on quality assessment techniques that indisputably reflect the merit of care delivered. Only measurable outcomes and metrics that are modifiable should be identified and collected.
Lloyd W Klein
doaj   +1 more source

Gas gun shock experiments with single-pulse x-ray phase contrast imaging and diffraction at the Advanced Photon Source

, 2012
The highly transient nature of shock loading and pronounced microstructure effects on dynamic materials response call for {\it in situ}, temporally and spatially resolved, x-ray-based diagnostics.
B. J. Jensen, Bowden F. P., D. E. Hooks, J. D. Yeager, K. Fezzaa, K. J. Ramos, K. Kwiatkowski, Kwiatkowski K., S. N. Luo, T. Shimada   +9 more
core   +1 more source