Percutaneous coronary intervention in the elderly: changes in case-mix and periprocedural outcomes in 31758 patients treated between 2000 and 2007 [PDF]
<p>Background: The elderly account for an increasing proportion of the population and have a high prevalence of coronary heart disease. Percutaneous coronary intervention (PCI) is the most common method of revascularization in the elderly.
Eteiba, H. +9 more
core +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma [PDF]
We investigated the cytotoxicity and biology of the novel broad-spectrum hydroxamic acid-based histone deacetylase inhibitor (HDACi), PCI-24781. PCI-24781 was studied alone and combined with bortezomib in Hodgkin lymphoma (L428) and non-Hodgkin's ...
Andrew Evens +9 more
core +1 more source
Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina +2 more
wiley +1 more source
Background: Major adverse cardiovascular events (MACEs) significantly affect the prognosis of patients with myocardial infarction (MI).
Yi Xiang +5 more
doaj +1 more source
Pompeo Colajanni e l’antifascismo in Sicilia. Un dialogo con Emanuele Macaluso
Emanuele Macaluso (1924-2021), a prominent exponent of the PCI, is interviewed by Carmelo Albanese on the figure of Pompeo Colajanni (1906-1987), one of the most important and well-known figures of the Italian Resistance.
Carmelo ALBANESE
doaj
Efficacy of Combined 5-Fluorouracil and Photodynamic Therapy in Glioma Spheroids
Standard treatment regimens consisting of surgery, radiation and chemotherapy have proven ineffective for the treatment of high-grade gliomas such as glioblastoma multiforme (GBM).
Singh, Karanjit
core +1 more source
A specified procedure for distress identification and assessment for urban road surfaces based on PCI [PDF]
In this paper, a simplified procedure for the assessment of pavement structural integrity and the level of service for urban road surfaces is presented.
Loprencipe, Giuseppe +1 more
core +2 more sources
A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong +13 more
wiley +1 more source
Bivalirudin versus unfractionated heparin: a meta-analysis of patients receiving percutaneous coronary intervention for acute coronary syndromes [PDF]
OBJECTIVE: Acute coronary syndrome (ACS) encompasses ST segment elevation myocardial infarction (STEMI), with generally high thrombus burden and non-ST segment elevation ACS (NSTE-ACS), with lower thrombus burden.
Farag, M +3 more
core +1 more source

