Results 111 to 120 of about 11,741,279 (272)

Osteoblasts on rod shaped hydroxyapatite nanoparticles incorporated pcl film provide an optimal osteogenic niche for stem cell differentiation

open access: yes, 2011
After the clinical insertion of a bone biomaterial, the surrounding osteoblasts would migrate and attach to the implant surface and foster a microenvironment that largely determines the differentiation fate of the comigrated mesenchymal stem cells ...
Hala Zreiqat   +7 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

open access: yesAdvanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen   +17 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Spanish version of the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) in health workers

open access: yesInternational Journal of Mental Health
Abstract Background The Posttraumatic Stress Disorder Checklist (PCL-5) is one of the most widely used instruments for assessing posttraumatic stress disorder (PTSD), adapted to meet DSM-5 criteria.
David Villarreal-Zegarra   +10 more
openaire   +1 more source

Adults PCL-5

open access: yes
Adults PCL-
Vasconcelos, Alina
core   +1 more source

Amphiphilic block copolymers : synthesis, self-assembly and applications [PDF]

open access: yes, 2015
Self-assembly of amphiphilic block copolymers in aqueous solution is one of the most important nanotechnological methods to prepare nanocarriers for different applications, such as drug delivery, biosensor, nanoreactor and so on. Synthesis of new types
Wu, Dalin
core   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

open access: yesAdvanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li   +9 more
wiley   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

open access: yesAdvanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li   +13 more
wiley   +1 more source

In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang   +5 more
wiley   +1 more source

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