Results 71 to 80 of about 31,907 (223)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Mechanism of Poria cocos Polysaccharide Regulating Autophagy and Chemotherapy Resistance of Hepatocellular Carcinoma Cells through LncRNAHCG11/miR-539-3p 539-3p

open access: yesShipin gongye ke-ji
Objective: To explore the effects and mechanism of Poria cocos polysaccharide (PCP) on proliferation, autophagy and chemotherapy resistance of hepatocellular carcinoma cells.
Yongfang CHEN, Yanke LI, Shujing ZHANG
doaj   +1 more source

Mycophenolate mofetil may protect against Pneumocystis carinii pneumonia in renal transplanted patients Micofenolato mofetil pode proteger contra a pneumonia por Pneumocystis carinii em transplantados renais

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2005
Pneumocystis carinii pneumonia (PCP) is usually prevented in transplanted patients by prophylactic trimethoprim-sulfamethoxazol (TMS). Mycophenolate mofetil (MMF) has been shown to have a strong protective effect against PCP in rats.
Luiz Sergio Azevedo   +4 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis

open access: yesArthritis Care &Research, EarlyView.
Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner   +12 more
wiley   +1 more source

Objective Data Reveals Gender Preferences for Patients’ Primary Care Physician

open access: yesJournal of Primary Care & Community Health, 2020
Background and Objectives: Most studies based on self-reported data indicate that female patients more often than males have a same-gender preference for their primary care physician (PCP).
Madelinn Fink   +7 more
doaj   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

Planar Cell Polarity Controls Pancreatic Beta Cell Differentiation and Glucose Homeostasis

open access: yesCell Reports, 2012
Planar cell polarity (PCP) refers to the collective orientation of cells within the epithelial plane. We show that progenitor cells forming the ducts of the embryonic pancreas express PCP proteins and exhibit an active PCP pathway.
Cedric Cortijo   +3 more
doaj   +1 more source

Formal and informal social care in people with Rheumatic and Musculoskeletal diseases: a cross‐sectional multicentre survey

open access: yesArthritis Care &Research, Accepted Article.
Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro   +6 more
wiley   +1 more source

Bioplastics from orange processing waste and poly(lactic acid)

open access: yesFuture Foods
Bioplastics have the potential to mitigate the aggravating crisis of plastic pollution. Valorizing agri-food side streams for such a purpose is particularly beneficial as it valorizes massively produced waste, thus contributing to the shift towards ...
Laís T. Possari   +6 more
doaj   +1 more source

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