Results 201 to 210 of about 1,169,901 (341)

Correcting PCR amplification errors in unique molecular identifiers to generate absolute numbers of sequencing molecules

, 2023
Sun J, Philpott M, Loi D, Li S, Monteagudo-Mesas P, Hoffman G, Robson J, Mehta N, Gamble V, Brown T, Sr TB, Canzar S, Oppermann U, Cribbs AP.   +13 more
europepmc   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Implementation of a Multiplex PCR Amplification System Combined With Next-Generation Genome Sequencing to Decipher the Circulation of Human Coronavirus 229E Lineages in Southern France. [PDF]

J Med Virol
Hikmat H, Py J, Boschi C, Burel E, Le Targa L, Million M, Lesage L, Morand A, La Scola B, Colson P.   +9 more
europepmc   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification. [PDF]

Heliyon
Lee D, Seo TS.
europepmc   +1 more source

Rapid and sensitive non-radioactive detection of mutant K-ras genes in clinical samples by mutant enriched PCR amplification

, 1995
Erik Kolbe, Magnus von Knebel Doeberitz
openalex   +2 more sources

Random priming PCR strategy to amplify and clone trace amounts of DNA [PDF]

, 2003
Nianxiang Zou, Susan E. Ditty, Bingjie Li, Shyh‐Ching Lo   +3 more
openalex   +1 more source

Mispriming and PCR amplification of hsp27

Cell Stress & Chaperones, 1997
F, Trautinger, C, Jantschitsch, R, Strohal, M, Pourmojib, I, Kindås-Mügge   +4 more
openaire   +3 more sources

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Automated post-run analysis of arrayed quantitative PCR amplification curves using machine learning. [PDF]

Gates Open Res
Brintz BJ, Operario DJ, Brown DG, Wu S, Wang L, Houpt ER, Leung DT, Liu J, Platts-Mills JA.   +8 more
europepmc   +1 more source