Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitope. [PDF]
PLoS Pathogens, 2019 Postweaning multisystemic wasting disease (PMWS) in piglets caused by porcine circovirus type 2 (PCV2) is one of the major threats to most pig farms worldwide.
Xiaobing Mo +5 more
doaj +4 more sources
The Positive Correlation of the Enhanced Immune Response to PCV2 Subunit Vaccine by Conjugation of Chitosan Oligosaccharide with the Deacetylation Degree [PDF]
Marine Drugs, 2017 Chitosan oligosaccharides (COS), the degraded products of chitosan, have been demonstrated to have versatile biological functions. In primary studies, it has displayed significant adjuvant effects when mixed with other vaccines.
Guiqiang Zhang +7 more
doaj +3 more sources
Strain-Dependent Porcine Circovirus Type 2 (PCV2) Entry and Replication in T-Lymphoblasts [PDF]
Viruses, 2019 Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD). PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte depletion in lymphoid tissues. PCV2 infection of lymphoblasts has not been studied.
Ruifang Wei +2 more
doaj +3 more sources
Cellular adaptive immune response against porcine circovirus type 2 in subclinically infected pigs [PDF]
BMC Veterinary Research, 2009 Background Porcine circovirus type 2 (PCV2) is a dominant causative agent of postweaning multisystemic wasting syndrome (PMWS), a multifactorial disease complex with putative immunosuppressive characteristics. Little is known about adaptive PCV2-specific
Gerber Heidi +4 more
doaj +3 more sources
Isolation, Genome Phylogenetic Analysis and In vitro Rescue of a Newly Emerging Porcine Circovirus Type 2 [PDF]
Pakistan Veterinary Journal, 2012 Porcine circovirus type 2 (PCV2) is the major causative agent of post-weaning multisystemic wasting syndrome (PMWS). Infection by PCV2 may cause heavy losses in pig industry.
Weijuan Zhu and Xiaofeng Ren*
doaj +2 more sources
Annexin A2 facilitates porcine circovirus type 2 infection by mediating viral attachment to host cells and interacting with the capsid protein [PDF]
Veterinary ResearchPorcine circovirus type 2 (PCV2) causes substantial economic losses globally. Although glycosaminoglycans (GAGs) have been identified as the general cell receptors responsible for PCV2 binding and subsequent cell infection, other critical protein(s) may ...
Yifan Jiang +12 more
doaj +2 more sources
Evaluation of PCV2 vaccine immunogenicity and efficacy using ELISpot to detect virus-specific memory B cells [PDF]
Porcine Health ManagementBackground Porcine Circovirus 2 (PCV2) vaccination plays a crucial role in preventing porcine circovirus-associated disease (PCVAD). Nevertheless, pig farms face significant challenges in evaluating vaccination efficacy due to the inability of PCV2 ...
Jie Fan +9 more
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Viruses, 2022 Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus (PCVs) are two major viruses that affect pigs. Coinfections between PRRSV and PCV2 are frequently reported in most outbreaks, with clinical presentations involving dyspnea,
Jinyong Zhang +12 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionA study in 2006 showed that the clinical course of PEDV disease was markedly aggravated by transplacental infection of PCV2. Therefore, we investigated whether the small intestine supports PCV2 replication and the effect of PCV2 infection on ...
Hao Zhang +10 more
doaj +1 more source
Viruses, 2023 Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus 2 (PCV2) are economically important pathogens in swine, and pigs with dual infections of PCV2 and PRRSV consistently have more severe clinical symptoms and interstitial ...
Zhiying Cui +8 more
doaj +1 more source