Results 1 to 10 of about 7,142 (175)

Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitope. [PDF]

PLoS Pathogens, 2019
Postweaning multisystemic wasting disease (PMWS) in piglets caused by porcine circovirus type 2 (PCV2) is one of the major threats to most pig farms worldwide.
Xiaobing Mo, Xiangdong Li, Bo Yin, Junhua Deng, Kegong Tian, Adam Yuan   +5 more
doaj   +2 more sources

Comparative Safety and Efficacy of Commercial Porcine Vaccines Against Mycoplasma hyopneumoniae and Porcine Circovirus Type 2 (PCV2) [PDF]

Animals
Mycoplasma hyopneumoniae (Mhyo) and porcine circovirus type 2 (PCV2) infections cause enormous economic losses in the swine production sector. Vaccination remains the most effective strategy against the complex clinical entities caused by these pathogens.
Meritxell Simon-Grifé, Alexandra Moros, Cecilia Pedernera, Ester Puigvert, Lucía Acal, Elena Plantalech, Mercè Roca, Jordi Montané, Ricard March, Marta Sitjà   +9 more
doaj   +2 more sources

Concomitant Infection With Porcine circovirus 2 and Porcine Epidemic Diarrhea Virus Does Not Increase Enteritis Severity in Experimentally Infected Weaned Piglets. [PDF]

Transbound Emerg Dis
Background Young pigs are often coinfected with porcine circovirus 2 (PCV2) and porcine epidemic diarrhea virus (PEDV). This study aimed to determine the impact of coinfection of pigs with PCV2 and PEDV. Forty 16‐day‐old crossbred mixed‐sex piglets were assigned to four groups (n = 10/group, NEG‐CONTROL, PCV2‐CONTROL, PCV2+PEDV, and PEDV‐CONTROL).
Gerber PF, Zhang J, Noel A, Wang B, Huang Y, Halbur PG, Opriessnig T.   +6 more
europepmc   +2 more sources

Development of Magnetic Particle-Based Chemiluminescence Immunoassays for Detecting PCV2 VLP- and Rep-Specific Antibodies and Their Combined Use for Immune Evaluation and Replication-Associated Exposure Assessment. [PDF]

Transbound Emerg Dis
Porcine circovirus 2 (PCV2) remains a major swine pathogen, and interpretation of capsid protein (Cap)–based serology is challenging in vaccinated populations because vaccine‐induced Cap antibodies overlap with replication‐associated serological signals.
Gou M, Song X, Fan J, Chen Z, Kuang Z, Lu M, Fan Z, Ge M.   +7 more
europepmc   +2 more sources

Engineered PCV2 VLPs for Antigen Delivery: A Platform for Next-Generation Veterinary Vaccines. [PDF]

Transbound Emerg Dis
The capsid (Cap) protein of porcine circovirus type 2 (PCV2) self‐assembles into virus‐like particles (VLPs) that form stable, noninfectious nanoparticles with T = 1 icosahedral symmetry. Mimicking native virion architecture, these VLPs display antigens in a highly ordered array, conferring strong immunogenicity for both humoral and cellular responses.
Ding P, Liu Y, Wang C, Wang A.
europepmc   +2 more sources

Synergistic Pathogenicity by Coinfection and Sequential Infection with NADC30-like PRRSV and PCV2 in Post-Weaned Pigs

Viruses, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus (PCVs) are two major viruses that affect pigs. Coinfections between PRRSV and PCV2 are frequently reported in most outbreaks, with clinical presentations involving dyspnea,
Jinyong Zhang, Peng Wang, Changzhan Xie, Zhuo Ha, Ning Shi, He Zhang, Zhuoxin Li, Jicheng Han, Yubiao Xie, Xiangshu Qiu, Yimo Tao, Ningyi Jin, Huijun Lu   +12 more
doaj   +1 more source

Immune Molecules’ mRNA Expression in Porcine Alveolar Macrophages Co-Infected with Porcine Reproductive and Respiratory Syndrome Virus and Porcine Circovirus Type 2

Viruses, 2023
Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus 2 (PCV2) are economically important pathogens in swine, and pigs with dual infections of PCV2 and PRRSV consistently have more severe clinical symptoms and interstitial ...
Zhiying Cui, Likun Zhou, Xingxing Hu, Shijie Zhao, Pengli Xu, Wen Li, Jing Chen, Yina Zhang, Pingan Xia   +8 more
doaj   +1 more source

Genetic association of polymorphisms in porcine RGS16 with porcine circovirus viral load in naturally infected Yorkshire pigs

Journal of Animal Science and Technology, 2021
Regulator of G protein signaling 16 (RGS16) is known to be associated with porcine circovirus type 2 (PCV2). PCV2 associated disease (PCVAD) is a serious problem in the swine industry. The representative symptoms
Seung-Hoon Lee, Kyu-Sang Lim, Ki-Chang Hong, Jun-Mo Kim   +3 more
doaj   +1 more source

Genetic Evolution Analysis of Porcine Circovirus Type 2 in Yunnan Province

Guangdong nongye kexue, 2022
【Objective】The study was carried out to investigate the prevalence of porcine circovirus Type 2 (PCV2) in pigs and cattle in Yunnan Province, and to identify the genetic variation and molecular evolution trend of PCV2 strains in Yunnan Province.【Method ...
Shuai HE, Yuzhu ZHANG, Nianci LYU, Yifang ZHANG, Jun CHAI   +4 more
doaj   +1 more source

Isolation and pathogenicity of porcine circovirus type 2 in mice from Guangxi province, China

Virology Journal, 2023
Background Porcine circovirus type 2 (PCV2), a member of the genus Circovirus and family Circoviridae, is a closed, small, circular, and single-stranded DNA virus, and it is a crucial swine pathogen of porcine circovirus-associated diseases (PCVADs ...
Qiulin Jiao, Liuyue Yang, Xiangzu Liu, Yanwen Wen, Linxing Tian, Ping Qian, Huanchun Chen, Xiangmin Li   +7 more
doaj   +1 more source