Results 11 to 20 of about 14,320 (287)

The Positive Correlation of the Enhanced Immune Response to PCV2 Subunit Vaccine by Conjugation of Chitosan Oligosaccharide with the Deacetylation Degree [PDF]

open access: yesMarine Drugs, 2017
Chitosan oligosaccharides (COS), the degraded products of chitosan, have been demonstrated to have versatile biological functions. In primary studies, it has displayed significant adjuvant effects when mixed with other vaccines.
Guiqiang Zhang   +7 more
doaj   +3 more sources

A Host Factor GPNMB Restricts Porcine Circovirus Type 2 (PCV2) Replication and Interacts With PCV2 ORF5 Protein [PDF]

open access: goldFrontiers in Microbiology, 2019
Porcine circovirus type 2 (PCV2) is the infectious agent of postweaning multisystemic wasting syndrome (PMWS). The recently discovered open reading frame 5 (ORF5) in PCV2 genome encodes a non-structural protein. Previous study revealed that ORF5 protein inhibits cell proliferation and may interact with host transmembrane glycoprotein NMB (GPNMB ...
Kangkang Guo   +10 more
openalex   +4 more sources

Detection and Complete Genome Analysis of Porcine Circovirus 2 (PCV2) and an Unclassified CRESS DNA Virus from Diarrheic Pigs in the Dominican Republic: First Evidence for Predominance of PCV2d from the Caribbean Region

open access: yesViruses, 2022
We report here high rates (47.5%, 48/101) of detection of porcine circovirus 2 (PCV2) in diarrheic pigs from three pig farms in the Dominican Republic.
Kerry Gainor   +5 more
doaj   +2 more sources

Strain-Dependent Porcine Circovirus Type 2 (PCV2) Entry and Replication in T-Lymphoblasts [PDF]

open access: yesViruses, 2019
Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD). PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte depletion in lymphoid tissues. PCV2 infection of lymphoblasts has not been studied.
Ruifang Wei   +2 more
doaj   +3 more sources

Molecular Epidemiology and Genetic Characterization of PCV2 Circulating in Wild Boars in Southwestern Ethiopia

open access: yesJournal of Tropical Medicine, 2022
Porcine circovirus type 2 (PCV2) is one of the most relevant infectious agents affecting domestic pigs. Recently, a surprising PCV2 genetic heterogenicity has been reported in Africa.
Dechassa Tegegne   +4 more
doaj   +2 more sources

The combined usage of Matrine and Osthole inhibited endoplasmic reticulum apoptosis induced by PCV2

open access: yesBMC Microbiology, 2020
Background Porcine circovirus type 2 (PCV2) is an important and common DNA virus that infect pig and can cause immunosuppression and induce apoptosis in the infected cells. To escape the host immune system, PCV2 constantly builds up complex mechanisms or
Yinlan Xu   +9 more
doaj   +2 more sources

A novel PCV2 ORF5-interacting host factor YWHAB inhibits virus replication and alleviates PCV2-induced cellular response

open access: greenVeterinary Microbiology, 2020
Porcine circovirus type 2 (PCV2) infection causes porcine circovirus associated diseases (PCVAD) worldwide. Identification of host factors that interact with viral proteins is a fundamental step to understand the pathogenesis of PCV2. Our previous study reported that ORF5, a newly identified PCV2 viral protein supports PCV2 replication and interacts ...
Kangkang Guo   +7 more
openalex   +4 more sources

Isolation, Genome Phylogenetic Analysis and In vitro Rescue of a Newly Emerging Porcine Circovirus Type 2 [PDF]

open access: yesPakistan Veterinary Journal, 2012
Porcine circovirus type 2 (PCV2) is the major causative agent of post-weaning multisystemic wasting syndrome (PMWS). Infection by PCV2 may cause heavy losses in pig industry.
Weijuan Zhu and Xiaofeng Ren*
doaj   +2 more sources

A Comparison of Pathogenicity and Virulence of Three Porcine Circovirus Type 2 (PCV2) Genotypes (a, b, and d) in Pigs Singularly Inoculated with PCV2 and Dually Inoculated with Mycoplasma hyopneumoniae and PCV2

open access: yesPathogens, 2021
The objective of this study was to compare the virulence of three different porcine circovirus type 2 (PCV2) genotypes (PCV2a, PCV2b, and PCV2d) in pigs infected with either one of these three PCV2 genotypes versus pigs dually inoculated with Mycoplasma ...
Taehwan Oh   +5 more
doaj   +2 more sources

PCV3 in Thailand: Molecular epidemiology and relationship with PCV2.

open access: yesTransboundary and Emerging Diseases, 2021
Porcine circovirus type 3 has been circulating throughout the world and since their first report, various clinical signs and disease developments have been documented.
Wansika Visuthsak   +10 more
semanticscholar   +3 more sources

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