Results 131 to 140 of about 2,849 (260)

EGFR gene amplification in IDH-wildtype glioblastomas: an integrative bioinformatic and histopathological analysis using immunohistochemistry and fluorescence in situ hybridization. [PDF]

Discov Oncol
Oukhdouch A, Zinbi B, Sellami S, Rais H.
europepmc   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

Advanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan, Chuqi Li, Qianhe Dai, Junlan Zhou, Lijiao Cao, Yuying Liu, Jinger Chen, Meiping Xiong, Yuhang Jiang, Xianchan Li   +9 more
wiley   +1 more source

Lectin-captured plasma microRNAs predict response and survival in patients with non-small cell lung cancer treated with nivolumab. [PDF]

Oncol Lett
Narusawa E, Nakano Y, Nakazawa S, Hori K, Ohtaki Y, Kawatani N, Yazawa T, Yoshikawa R, Numajiri K, Kuriyama R, Kurokawa H, Taguchi Y, Mostafavi Zadeh SM, Okami H, Shiraishi T, Nakazawa N, Igarashi T, Kaira K, Saeki H, Shirabe K, Yokobori T.   +20 more
europepmc   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Accurate and Sensitive UHPLC-Tandem Mass Spectrometry Sequential Methods for Therapeutic Drug Monitoring of Aztreonam/Avibactam in Human Plasma. [PDF]

Pharmaceutics
Trozzi I, Giorgi B, De Paola R, Gatti M, Pea F.   +4 more
europepmc   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

Overview of Monitoring, Diagnostics, Aging Analysis, and Maintenance Strategies in High-Voltage AC/DC XLPE Cable Systems. [PDF]

Sensors (Basel)
Emdadi K, Gandomkar M, Aranizadeh A, Vahidi B, Mirmozaffari M.   +4 more
europepmc   +1 more source

A High‐Entropy Strategy for Chemoresistive Ethanol Sensors With Remarkably Rapid and Selective Response

Advanced Science, EarlyView.
The configurational‐entropy strategy enables rapid and sensitive ethanol detection using a multicomponent oxide. The high‐entropy (InSnFeZnW)Ox provides enriched oxygen vacancies and diverse adsorption sites that strengthen surface reactivity. The sensor achieves a 5135% ethanol response with fast kinetics and stable long‐term operation.
Gi Baek Nam, Jin Ho Seo, Youngmin Kim, Hyuk Jin Kim, Yeong Jae Kim, Seon Ju Park, YunKyung Kim, Hyeon‐Min Yu, Jiwoo Lee, Ji Hyeon Lim, Jiheon Lim, Jong Hun Kang, WooChul Jung, Jong Jin Jung, Jeong Woo Han, Seung Eon Moon, Seong Ju Hwang, Jong‐Hoon Kang, Zhigang Zhu, Ho Won Jang   +19 more
wiley   +1 more source

Nrf2/NOX2 Pathway Dysregulation and Oxidative Stress Biomarkers in Gaucher Disease-Associated Parkinsonism: Insights Into a Potential Therapeutic Target. [PDF]

J Cell Mol Med
Ardizzone A, Lanza M, Capra AP, Casili G, Bulzomì M, Luca F, Paterniti I, Campolo M, Esposito E.   +8 more
europepmc   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source