An immunoassay for the quantification of phosphorylated α-synuclein at serine 129 in human cerebrospinal fluid. [PDF]
Silva AM, Hickford ES, Cutler P.
europepmc +1 more source
Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li +9 more
wiley +1 more source
Two Comprehensive Liquid Chromatography High-Resolution Mass Spectrometry (UPLC-MS/MS) Multi-Methods for Real-Time Therapeutic Drug Monitoring (TDM) of Five Novel Beta-Lactams and of Fosfomycin Administered by Continuous Infusion. [PDF]
Trozzi I +4 more
europepmc +1 more source
Emerging Memory and Device Technologies for Hardware‐Accelerated Model Training and Inference
This review investigates the suitability of various emerging memory technologies as compute‐in‐memory hardware for artificial intelligence (AI) applications. Distinct requirements for training‐ and inference‐centric computing are discussed, spanning device physics, materials, and system integration.
Yoonho Cho +6 more
wiley +1 more source
Long COVID involves activation of proinflammatory and immune exhaustion pathways. [PDF]
Aid M +9 more
europepmc +1 more source
ABSTRACT With the continuous development of computer image processing, developing efficient and low‐power computing devices has become a key challenge. Memristors have integrated in‐situ storage and computing capabilities, making them an ideal choice for low‐power image processing computing architectures. However, current memristors are confronted with
Tengyu Li +4 more
wiley +1 more source
Cytotoxic Potential Evaluation of Innovative Pressurised Cyclic Solid-Liquid Extracts from <i>Withania somnifera</i>. [PDF]
Culurciello R +9 more
europepmc +1 more source
The integration of ultra‐flexible, all‐organic, field‐effect transistor‐based strain sensors to soft structures is reported for the development of sensorized soft robots. The envisaged application is the development of next‐generation, controllable, and observable soft robotic catheters for endoscopic applications, such as drug delivery. Mechanical and
Usama Mahmood +5 more
wiley +1 more source
Berberine from Tibetan Medicine <i>Dracocephalum tanguticum</i> Maxim Suppresses Colorectal Tumor Growth and Inhibits CD8⁺ T Cells Ferroptosis via the NRF2-SLC7A11-GPX4 Axis. [PDF]
Wang Y, Zhang Y, Wang Q, Zheng L, Liu Y.
europepmc +1 more source
This work presents a dual‐band photodetector based on the large‐scale, precise synthesis of Cs2AgBiBr6 single crystals. A rapid and efficient synthesis method is demonstrated, yielding high‐quality Cs2AgBiBr6 crystals with an average size of 2 × 2 × 1.5 mm3 and a production yield of 12.66%.
Yezhan Li +9 more
wiley +1 more source

