Results 201 to 210 of about 272,841 (277)

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

open access: yesChemistry – A European Journal, EarlyView.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Polydopamine‐Mediated Grafting of Cationic Polymer Brushes for Adsorption of Fluorinated Compounds

open access: yesChemistry – A European Journal, EarlyView.
We introduce a versatile approach to fabricate tunable charged interfaces by functionalizing stonewool fibers with a polydopamine (PDA)–quaternary amine coating via a grafting‐to method. The modified surfaces exhibit rapid, concentration‐dependent adsorption of anionic species driven by electrostatic interactions.
Agnes C. Morrissey   +9 more
wiley   +1 more source

Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Fezolinetant is a first‐in‐class, selective, non‐hormonal, neurokinin 3 receptor antagonist that is approved for the treatment of moderate to severe vasomotor symptoms due to menopause. In a phase 2b clinical study (n = 352), nine study participants experienced elevations in serum transaminases exceeding three times the upper limit of normal.
Jace C. Nielsen   +11 more
wiley   +1 more source

Identification and Structural Elucidation of a New Synthetic Cannabinoid, MDMB‐5′Br‐PINACA, in Seized Herbal Materials

open access: yesDrug Testing and Analysis, EarlyView.
MDMB‐5Br‐PINACA, a novel synthetic cannabinoid, was identified and structurally characterized in seized herbal products using GC‐MS, LC‐HRMS, and NMR. The discovery underscores ongoing diversification of SCs and the need for vigilant surveillance.
Alexandre Barcia de Godoi   +6 more
wiley   +1 more source

Rapid photocontrollable dopamine polymerization for instant adaptive wet adhesion. [PDF]

open access: yesNat Commun
Lu Z   +9 more
europepmc   +1 more source

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