Results 41 to 50 of about 1,493 (183)

Development of PDC Bit with Axe-shaped Teeth and its Application in East China Sea

open access: yesShiyou jixie, 2021
The PDC bits used in many wells in the East China Sea had low ROP and small footage in the process of drilling deep formation. After the bits were pulled out, it was found that the cutting teeth had been worn severely.
Li Qian   +5 more
doaj  

Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Cultured white adipocytes exposed to 31°C undergo cell‐autonomous metabolic adaptation characterized by enhanced mitochondrial function and widespread remodeling of the mitochondrial acetylome. Acetyl‐proteomic and metabolomic profiling identified mitochondria‐associated proteins, including SHMT2 and PCCA, whose acetylation changes were linked to ...
Hiroyuki Mori   +11 more
wiley   +1 more source

Conglomerate Rock Breaking Technology with New PDC Cutter and Its Application

open access: yesShiyou jixie, 2019
In oil and gas drilling, PDC bit has become an indispensable downhole tool for rock breaking. However, conglomerate formation is still the restricted area for PDC bit. At present, most of conglomerate formations are drilled using roller cone bit.
Zhu Xiaolin   +5 more
doaj  

PDC cutter pressure on plastic-brittle rock in the process of its destruction

open access: yesЗаписки Горного института, 2020
Presently, there are no methods for calculating the parameters of the drilling practices with rock-cutting tools equipped with polycrystalline diamond composite (PDC cutters). To create such a method requires the studying their work. The article presents
Oleg B. Trushkin, Hamzja I. Akchurin
doaj   +1 more source

Harnessing Tumor‐Specific Transcript Diversity Uncovers a Shared Neoantigen Reservoir for Pancreatic Ductal Adenocarcinoma

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This study introduces NeoAPP, a computational tool revealing that transcriptional dysregulation generates a dominant reservoir of neoantigens from tumor‐specific transcripts (TSTs) in pancreatic ductal adenocarcinoma (PDAC), far exceeding those of mutational origin.
Jingjing Zhao   +14 more
wiley   +1 more source

Optimization of Hydraulic Structure of Rotary Cutting PDC Bit

open access: yesShiyou jixie, 2020
Few researches have been conducted on the hydraulic structure optimization design of rotary cutting PDC bit. Standard k-ε model and discrete phase model (DPM) are used to simulate the bottom hole flow field of rotary cutting PDC bit and optimize the ...
Cao Yang, Zhang Boyu
doaj  

Transfer Printing and Reconfiguration of Soft Electronics Using Digital Microfluidics and Laser Machining

open access: yesAdvanced Functional Materials, Volume 36, Issue 56, 13 July 2026.
This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen   +15 more
wiley   +1 more source

New Bit with Rolling PDC Cutter

open access: yesShiyou jixie, 2016
The new rolling PDC cutter drill bit technology could effectively address the fixed cutter eccentric wear issue,prolong durability,improve ROP,resulting in improved drilling efficiency and reduced drilling costs,which is a great step of drill bit ...
Shi Jiangang   +4 more
doaj  

Numerical Simulation of the Flow Field of the PDC Bit Supporting the Pulse Jet Based ROP Improvement Tool

open access: yesShiyou jixie, 2020
In order to give full play to the performance of the ROP improvement tool based on pulsed downhole alternating flow field, this paper studied its support PDC bit by means of numerical simulation.
Fan Jiqiang   +5 more
doaj  

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu   +18 more
wiley   +1 more source

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