Results 101 to 110 of about 25,103 (218)

Sex‐Dependent Alterations in Behavioral Development of Mice Lacking α5‐Nicotinic Acetylcholine Receptors

open access: yesJournal of Neuroscience Research, Volume 104, Issue 10, October 2026.
Loss of α5‐nAChRs drives age‐dependent, sex‐specific behavioral alterations, with females showing early cognitive deficits and males a progressive decline. These findings identify α5‐nAChRs as key regulators of neural circuit maturation and underscore the critical importance of incorporating sex as a biological variable in preclinical research ...
Danai Papavranoussi Daponte   +3 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Diagnostic performance of narrow-band imaging and photodynamic diagnosis compared to white light cystoscopy for non-muscle invasive bladder cancer: A network meta-analysis of randomized trials

open access: yesInvestigative and Clinical Urology
Purpose: To compare the diagnostic performance of white light cystoscopy (WLC), photodynamic diagnosis (PDD), and narrow-band imaging (NBI) in the detection of non-muscle invasive bladder cancer (NMIBC) through a network meta-analysis of randomized ...
Se Young Choi   +8 more
doaj   +1 more source

A two‐stage framework for fast proton spot map generation in pencil beam scanning prostate SBRT planning

open access: yesMedical Physics, Volume 53, Issue 10, October 2026.
Abstract Background In pencil beam scanning (PBS) proton therapy, treatment plans are encoded as proton spot maps (PSMs). Although deep‐learning methods can rapidly predict three‐dimensional (3D) dose distributions from patient anatomy and planning intent, there is still no widely adopted direct, non‐iterative approach to convert doses into physically ...
Xueyan Tang   +8 more
wiley   +1 more source

Cell and small animal models for phenotypic drug discovery

open access: yesDrug Design, Development and Therapy, 2017
Mihaly Szabo,1 Sara Svensson Akusjärvi,1 Ankur Saxena,1 Jianping Liu,2 Gayathri Chandrasekar,1 Satish S Kitambi1 1Department of Microbiology Tumor, and Cell Biology, 2Department of Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden ...
Szabo M   +5 more
doaj  

Balancing d‐π/d‐π* Interactions: Valence‐Engineered Pd/TiO2 for Photocatalytic Acetylene Semi‐Hydrogenation

open access: yesRare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Photocatalytic acetylene (C2H2) semihydrogenation is a green route for ethylene (C2H4) production, yet the activity–selectivity trade‐off caused by imbalanced adsorption/activation of reactants and products remains a core challenge. Herein, we realize precise regulation of Pd oxidation states (Pd0, Pdδ+, and Pd2+) on anatase TiO2 nanocubes via
Zhidan Wang   +7 more
wiley   +1 more source

APPLICATIONS OF THE PDD-1

open access: yes
This paper investigates a novel application of the Perpendicular Distance Determinant (PDD-1): calculating triangle altitudes using only the lengths of the triangle's sides. The chapter presents a case-based analysis to demonstrate the PDD-1's effectiveness in determining altitude placement and length.
openaire   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

open access: yesChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales   +7 more
wiley   +1 more source

Hydrogen From Simulated Seawater Using Long‐Term Stable and Cost‐Effective Plasmonic Photocatalysts

open access: yesChemSusChem, Volume 19, Issue 18, 28 September 2026.
Can plasmonic photocatalysts withstand a saline environment? Yes! A conductive polyaniline shell stabilizes gold–silver nanoparticles while largely preserving charge transfer to TiO2, achieving 348 ± 108 μmol H2 g−1 h−1. Moreover, the catalyst survived 1 month of storage in simulated seawater, with almost full retention of its initial activity.
Fons Dingenen   +7 more
wiley   +1 more source

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