Results 101 to 110 of about 25,103 (218)
Loss of α5‐nAChRs drives age‐dependent, sex‐specific behavioral alterations, with females showing early cognitive deficits and males a progressive decline. These findings identify α5‐nAChRs as key regulators of neural circuit maturation and underscore the critical importance of incorporating sex as a biological variable in preclinical research ...
Danai Papavranoussi Daponte +3 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Purpose: To compare the diagnostic performance of white light cystoscopy (WLC), photodynamic diagnosis (PDD), and narrow-band imaging (NBI) in the detection of non-muscle invasive bladder cancer (NMIBC) through a network meta-analysis of randomized ...
Se Young Choi +8 more
doaj +1 more source
Abstract Background In pencil beam scanning (PBS) proton therapy, treatment plans are encoded as proton spot maps (PSMs). Although deep‐learning methods can rapidly predict three‐dimensional (3D) dose distributions from patient anatomy and planning intent, there is still no widely adopted direct, non‐iterative approach to convert doses into physically ...
Xueyan Tang +8 more
wiley +1 more source
Cell and small animal models for phenotypic drug discovery
Mihaly Szabo,1 Sara Svensson Akusjärvi,1 Ankur Saxena,1 Jianping Liu,2 Gayathri Chandrasekar,1 Satish S Kitambi1 1Department of Microbiology Tumor, and Cell Biology, 2Department of Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden ...
Szabo M +5 more
doaj
ABSTRACT Photocatalytic acetylene (C2H2) semihydrogenation is a green route for ethylene (C2H4) production, yet the activity–selectivity trade‐off caused by imbalanced adsorption/activation of reactants and products remains a core challenge. Herein, we realize precise regulation of Pd oxidation states (Pd0, Pdδ+, and Pd2+) on anatase TiO2 nanocubes via
Zhidan Wang +7 more
wiley +1 more source
This paper investigates a novel application of the Perpendicular Distance Determinant (PDD-1): calculating triangle altitudes using only the lengths of the triangle's sides. The chapter presents a case-based analysis to demonstrate the PDD-1's effectiveness in determining altitude placement and length.
openaire +1 more source
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales +7 more
wiley +1 more source
Personalized drug discovery from rare diseases to cancer. [PDF]
Katanaev VL.
europepmc +1 more source
Hydrogen From Simulated Seawater Using Long‐Term Stable and Cost‐Effective Plasmonic Photocatalysts
Can plasmonic photocatalysts withstand a saline environment? Yes! A conductive polyaniline shell stabilizes gold–silver nanoparticles while largely preserving charge transfer to TiO2, achieving 348 ± 108 μmol H2 g−1 h−1. Moreover, the catalyst survived 1 month of storage in simulated seawater, with almost full retention of its initial activity.
Fons Dingenen +7 more
wiley +1 more source

