Results 91 to 100 of about 174,626,138 (254)

zwicker-group/py-pde: 0.32.1

, 2023
<p>Fixed problem with setting allowed python versions</p> What's Changed <ul> <li>Fix requirements for maximal python version by @david-zwicker in <a href="https://github.com/zwicker-group/py-pde/pull/430">https://github.com/
Diego Volpatto, JKrausser, noah-ziethen, Juanjo Bazán, David Zwicker, Daniel S. Katz, lmenou, Estefania Vidal   +7 more
core   +1 more source

Research progress and current status of dynamic wave propagation characteristics in rock mass: A review

Deep Underground Science and Engineering, EarlyView.
This review elucidates the velocity–dispersion–attenuation coupling mechanisms of wave propagation in rock masses, compares six representative models, and reveals how pressure, temperature, mineral composition, and anisotropy jointly control dynamic responses in complex geological media.
Jiajun Shu, Tao Li, Ruiqi Yuan, Yue Li, Bingni Wu, Bo Liu, Zhengding Deng, Galindo Rubén, Fausto Molina‐Gómez   +8 more
wiley   +1 more source

Multi‐factor coupling effects in hydraulic fracturing of laminated shale: Experimental insights and physics‐informed neural network‐driven optimization

Deep Underground Science and Engineering, EarlyView.
This study establishes a multi‐factor coupling framework for predicting breakdown pressure in laminated shale by integrating experimental hydraulic fracturing tests, physics‐informed neural networks (PINNs), and Sobol sensitivity analysis. It reveals how differential stress, the bedding dip angle, and the injection rate interact to influence fracture ...
Tao Wang, Guoyao Xu, Liyuan Liu, Yao Zhang, Sitao Zhu, Hongyang Chu, Kaikai Zhao   +6 more
wiley   +1 more source

Cost Breakeven Point of Offshore Wind Energy in Brazil

Energies
Brazil has abundant natural resources and a largely renewable electricity matrix, with about 90% of its capacity from clean sources. Despite strong offshore wind potential, its economic viability remains uncertain due to the lack of a domestic supply ...
Rodrigo Vellardo Guimarães, Milad Shadman, Saulo Ribeiro Silva, Segen F. Estefen, Maurício Tiomno Tolmasquim, Amaro Olimpio Pereira   +5 more
doaj   +1 more source

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber   +15 more
wiley   +1 more source

First-Principles Modeling of an Electrolytic Cell for Lithium Hydroxide Production: A Multiscale ODE-PDE Framework

ChemEngineering
This study presents a first-principles dynamic model for the electrochemical production of lithium hydroxide (LiOH) in a bench-scale cation exchange membrane (CEM) cell. Its distinguishing feature is a single, dynamically coupled description of the whole
Belmiro P. M. Duarte, Nuno M. C. Oliveira   +1 more
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Digital twin framework for precision downy mildew intervention in greenhouses using intelligent air quality sensing

Cogent Food & Agriculture
Greenhouse cucumber production in the Shanxi region is persistently threatened by downy mildew (Pseudoperonospora cubensis), a fungal pathogen promoted by complex environmental factors including adverse AQI values, high humidity, and pronounced ...
Shikang Wu
doaj   +1 more source

Differential expression and function of PDE8 and PDE4 in effector T cells: Implications for PDE8 as a drug target in inflammation.

Frontiers in Pharmacology, 2016
Abolishing the inhibitory signal of intracellular cAMP is a prerequisite for effector T (Teff) cell function. The regulation of cAMP within leukocytes critically depends on its degradation by cyclic nucleotide phosphodiesterases (PDEs).
Amanda G. Vang, Amanda G. Vang, Hongli Dong, Rebecca K. Nguyen, Chaitali Basole, William Housley, William Housley, Linda Guernsey, Alexander J Adami, Roger Thrall, Robert Bennett Clark, Paul Mark Epstein, Stefan Brocke   +12 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source