Results 31 to 40 of about 174,626,138 (254)
Type-4 Phosphodiesterase (PDE4) Blockade Reduces NETosis in Cystic Fibrosis
Neutrophilic inflammation is a key determinant of cystic fibrosis (CF) lung disease. Neutrophil-derived free DNA, released in the form of extracellular traps (NETs), significantly correlates with impaired lung function in patients with CF, underlying ...
Licia Totani +14 more
doaj +1 more source
<p>This is mostly a maintenance release, fixing some important bugs.</p> What's Changed <ul> <li>Use is_jitted to check for compiled function by @david-zwicker in <a href="https://github.com/zwicker-group/py-pde/pull/378"> ...
Diego Volpatto +7 more
core +1 more source
The article discusses an approach to modeling thermodynamic processes in food industry production systems using MATLAB PDE Toolbox. The main goal of the research is to create digital twins that allow simulating thermal processes and optimizing production
K. Makhambetov +2 more
doaj +1 more source
Distributed parameter systems (DPS) widely exist in the large-scale industrial production industry. Techniques developed for DPS can further demonstrate the complexity of the industrial process, such as the hot-rolled strip laminar cooling (HSLC) process.
Jie Dong +3 more
doaj +1 more source
What's Changed Minor improvements by @david-zwicker in https://github.com/zwicker-group/py-pde/pull/308 Improved documentation by @david-zwicker in https://github.com/zwicker-group/py-pde/pull/313 Adjusted to newer numba_mpi by @david-zwicker in https://
Diego Volpatto +7 more
core +1 more source
This study reports a self‐powered InGaAs nanowire photodetector achieving single‐photon‐level sensitivity in the shortwave infrared at non‐cryogenic temperatures. The device demonstrates high‐speed imaging capabilities even under extremely low‐flux conditions.
Kosala Dhanawansha +10 more
wiley +1 more source
A yeast-based chemical screen identifies a PDE inhibitor that elevates steroidogenesis in mouse Leydig cells via PDE8 and PDE4 inhibition. [PDF]
A cell-based high-throughput screen (HTS) was developed to detect phosphodiesterase 8 (PDE8) and PDE4/8 combination inhibitors. By replacing the Schizosaccharomyces pombe PDE gene with the murine PDE8A1 gene in strains lacking adenylyl cyclase, we ...
Didem Demirbas +5 more
doaj +1 more source
What's Changed Treat NaN in state space in adaptive time stepping by @david-zwicker in https://github.com/zwicker-group/py-pde/pull/239 Added improved adaptive stepper for runge-kutta method by @david-zwicker in https://github.com/zwicker-group/py-pde ...
Diego Volpatto +7 more
core +1 more source
Zero‐Waste Manufacturing of Ophthalmic Lenses by Direct Fluidic Shaping in Arbitrary Domains
Conventional ophthalmic lens manufacturing discards up to 97% of material through subtractive processes. The Cookie Cutter algorithm extends Fluidic Shaping to arbitrary rim geometries. The framework prescribes a spatially varying boundary height that, under neutral buoyancy and surface tension, shapes curable polymer into spherocylindrical lenses that
Yotam Katzman +6 more
wiley +1 more source
The bacterial second messenger bis-(3′-5′)-cyclic diguanosine monophosphate (c-di-GMP) ubiquitously promotes bacterial biofilm formation. Intracellular pools of c-di-GMP seem to be dynamically negotiated by diguanylate cyclases (DGCs, with GGDEF domains)
Olga Sarenko +7 more
doaj +1 more source

