Results 241 to 250 of about 225,423 (289)
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Phosphodiesterases (PDEs) and PDE inhibitors for treatment of LUTS
Neurourology and Urodynamics, 2007Lower urinary tract (LUT) smooth muscle can be relaxed by drugs that increase intracellular concentrations of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Both of these substances are degraded by phosphodiesterases (PDEs), which play a central role in the regulation of smooth muscle tone.
Karl-Erik, Andersson +3 more
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2020
Summary: In this paper we study a number of nonlinear fractional equations, involving Caputo derivative in space or/and in time, admitting explicit solution in separating variable form. Some of these equations are particularly interesting because they admit completely periodic solutions. When time-fractional derivatives are introduced, this property is
Riccardo Droghei, Roberto Garra
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Summary: In this paper we study a number of nonlinear fractional equations, involving Caputo derivative in space or/and in time, admitting explicit solution in separating variable form. Some of these equations are particularly interesting because they admit completely periodic solutions. When time-fractional derivatives are introduced, this property is
Riccardo Droghei, Roberto Garra
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Proceedings of the 2017 ACM SIGSIM Conference on Principles of Advanced Discrete Simulation, 2017
In this paper, we present initial experiences implementing a general Parallel Discrete Event Simulation (PDES) accelerator on a Field Programmable Gate Array (FPGA). The accelerator can be specialized to any particular simulation model by defining the object states and the event handling logic, which are then synthesized into a custom accelerator for ...
Shafiur Rahman +2 more
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In this paper, we present initial experiences implementing a general Parallel Discrete Event Simulation (PDES) accelerator on a Field Programmable Gate Array (FPGA). The accelerator can be specialized to any particular simulation model by defining the object states and the event handling logic, which are then synthesized into a custom accelerator for ...
Shafiur Rahman +2 more
openaire +1 more source
2014
We first review the linear Laplace equation. For functions $$\phi\;:\;\mathbb{R}^n\;\rightarrow\;\mathbb{R}$$ we define the Lagrangian $$ L^e(\phi)\;=\;\frac{1} {2}\int_{\mathbb{R}^{n}} {\left| {\nabla _x \phi } \right|^2 \,dx} \, = \,\frac{1} {2}\int_{\mathbb{R}^{n}} {\partial _\alpha \phi } \cdot \partial _\alpha \phi \,dx ,$$ with the ...
Herbert Koch +2 more
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We first review the linear Laplace equation. For functions $$\phi\;:\;\mathbb{R}^n\;\rightarrow\;\mathbb{R}$$ we define the Lagrangian $$ L^e(\phi)\;=\;\frac{1} {2}\int_{\mathbb{R}^{n}} {\left| {\nabla _x \phi } \right|^2 \,dx} \, = \,\frac{1} {2}\int_{\mathbb{R}^{n}} {\partial _\alpha \phi } \cdot \partial _\alpha \phi \,dx ,$$ with the ...
Herbert Koch +2 more
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Hydrophobic Tagging-Induced Degradation of PDEδ in Colon Cancer Cells
ACS Medicinal Chemistry Letters, 2022Yu Li, Guoqiang Dong, Chunquan Sheng
exaly
Compensating PDE actuator and sensor dynamics using Sylvester equation
Automatica, 2021Vivek Natarajan
exaly
1991
The main purpose of this interesting paper is to generalize to higher order PDE's some previous results of \textit{J. Eliashberg} [Semin. sud- rhodanien géom. I, 17-31 (1984; Zbl 0542.57024)] concerning the cobordism of the first order PDE's. The paper contains two sections (1. Cobordism and spectral sequences; 2.
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The main purpose of this interesting paper is to generalize to higher order PDE's some previous results of \textit{J. Eliashberg} [Semin. sud- rhodanien géom. I, 17-31 (1984; Zbl 0542.57024)] concerning the cobordism of the first order PDE's. The paper contains two sections (1. Cobordism and spectral sequences; 2.
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Development of a PDEδ‐Targeting PROTACs that Impair Lipid Metabolism
Angewandte Chemie - International Edition, 2020Michael Winzker +2 more
exaly
PDE-constrained models with neural network terms: Optimization and global convergence
Journal of Computational Physics, 2023Konstantinos Spiliopoulos
exaly