Results 151 to 160 of about 4,657 (257)

Distinct Roles of PDE4 and PDE10A in the Regulation of cAMP/PKA Signaling in the Striatum [PDF]

, 2008
Akinori Nishi, Mahomi Kuroiwa, Diane B. Miller, James P. O’Callaghan, Helen S. Bateup, Takahide Shuto, Naoki Sotogaku, Takaichi Fukuda, Nathaniel Heintz, Paul Greengard, Gretchen L. Snyder   +10 more
openalex   +1 more source

Single-nucleus transcriptomics reveals disease- and pathology-specific signatures in α-synucleinopathies. [PDF]

Brain
Nido GS, Castelli M, Mostafavi S, Rubiolo A, Shadad O, Alves G, Tysnes OB, Flønes IH, Dölle C, Tzoulis C.   +9 more
europepmc   +1 more source

PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA [PDF]

, 2020
Matthias Lambert, Janelle M. Spinazzola, Jeffrey J. Widrick, Anna Pakuła, James R. Conner, Janice E. Chin, Jane Owens, Louis M. Kunkel   +7 more
openalex   +1 more source

Novel potential neuroprotective targets for DengZhanXiXin injection in middle cerebral artery occlusion rats recommended by quantitative proteomics and simulated docking. [PDF]

Front Neurosci
Li M, Wang L, An H, Li X, Chen Y, Wei D, Zhang Z.   +6 more
europepmc   +1 more source

Targeting Striatal Glutamate and Phosphodiesterases to Control L-DOPA-Induced Dyskinesia. [PDF]

Cells, 2023
Kochoian BA, Bure C, Papa SM.
europepmc   +1 more source

Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility

, 2014
Robert M. Rzasa, Michael Frohn, Kristin L. Andrews, Samer Chmait, Ning Chen, Jeffrey Clarine, Carl D. Davis, Heather Eastwood, Daniel B. Horne, Essa Hu, Adrie Jones, Matthew R. Kaller, Roxanne K. Kunz, Silke Miller, Holger Monenschein, Thomas T. Nguyen, Alexander J. Pickrell, Amy C. Porter, Andreas Reichelt, Xiaoning Zhao, James Treanor, Jennifer R. Allen   +21 more
openalex   +2 more sources

Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain [PDF]

, 2011
Zhude Tu, Jinda Fan, Shihong Li, Lynne A. Jones, Jinquan Cui, Prashanth K. Padakanti, Jinbin Xu, Dexing Zeng, Kooresh I. Shoghi, Joel S. Perlmutter, Robert H. Mach   +10 more
openalex   +1 more source

Transcriptome analysis of chicken fibroblast following transforming growth factor β1-mediated activation. [PDF]

Poult Sci
Hou T, Zhang L, Zhao L, Gao F, Xing T.
europepmc   +1 more source

De Novo Mutations in PDE10A Cause Childhood-Onset Chorea with Bilateral Striatal Lesions

, 2016
Niccolò E. Mencacci, Erik-Jan Kamsteeg, Kosuke Nakashima, Lea R’Bibo, David S. Lynch, Bettina Balint, Michèl A.A.P. Willemsen, Matthew Adams, Sarah Wiethoff, Kazunori Suzuki, Ceri H. Davies, Joanne Ng, Esther Meyer, Liana Veneziano, Paola Giunti, Deborah Hughes, F. Lucy Raymond, Miryam Carecchio, Giovanna Zorzi, Nardo Nardocci, Chiara Barzaghi, Barbara Garavaglia, Vincenzo Salpietro, John Hardy, Alan Pittman, Henry Houlden, Manju A. Kurian, Haruhide Kimura, Lisenka E.L.M. Vissers, Nicholas Wood, Kailash P. Bhatia   +30 more
openalex   +1 more source

In Vivo Assessment and Dosimetry of 2 Novel PDE10A PET Radiotracers in Humans: ¹⁸F-MNI-659 and ¹⁸F-MNI-654 [PDF]

, 2014
Olivier Barret, David Thomae, Adriana Tavares, David Alagille, Caroline Papin, Rikki N. Waterhouse, Timothy J. McCarthy, Danna Jennings, Kenneth Marek, David Russell, John Seibyl, Gilles Tamagnan   +11 more
openalex   +1 more source