Results 151 to 160 of about 4,135 (194)

Inhalable Carbonyl Sulfide Donor-Hybridized Selective Phosphodiesterase 10A Inhibitor for Treating Idiopathic Pulmonary Fibrosis by Inhibiting Tumor Growth Factor-β Signaling and Activating the cAMP/Protein Kinase A/cAMP Response Element-Binding Protein (CREB)/p53 Axis. [PDF]

ACS Pharmacol Transl Sci
Wang Q, Liu X, Yuan H, Zhang F, Wu J, Yang D, Qian J, Huang YY, Chai G, Luo HB, Guo L.   +10 more
europepmc   +1 more source

Highlights lecture EANM 2014: “Gimme gimme gimme those nuclear Super Troupers” [PDF]

, 2015

core   +1 more source

Transcriptome analysis of chicken fibroblast following transforming growth factor β1-mediated activation. [PDF]

Poult Sci
Hou T, Zhang L, Zhao L, Gao F, Xing T.
europepmc   +1 more source

Bmal1 Modulates Striatal cAMP Signaling and Motor Learning. [PDF]

J Neurosci
Cryan CE, Liao Y, Widjaja JH, Sloan DC, Han Q, Rudic RD, Muntean BS.   +6 more
europepmc   +1 more source

Cloning and Characterization of a Novel Human Phosphodiesterase That Hydrolyzes Both cAMP and cGMP (PDE10A)

, 1999
Kotomi Fujishige, Jun Kotera, Hideo Michibata, Keizo Yuasa, Shin‐ichiro Takebayashi, Katsuzumi Okumura, Kenji Omori   +6 more
openalex   +1 more source

Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer. [PDF]

J Med Chem
Haines BJ, Kreamer M, Benej M, Mohammed S, Bridge H, Bayrali-Ulker E, Fergatova A, Williams TM, Li Z, Papandreou I, Denko NC, Mitton-Fry MJ.   +11 more
europepmc   +1 more source

Dual PDE4/10A inhibition restores CREB1 function and enhances neuronal resilience in models of alzheimer's disease. [PDF]

Alzheimers Res Ther
Rong X, Yao X, Fang H, Saji J, Qian Y, Gu JX, Yang MY, Wei P, Liu CR, Chen B, Zhao PP, Cheung CL, Bo L, Zheng HF.   +13 more
europepmc   +1 more source

Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A)

, 2014
Essa Hu, Kristin L. Andrews, Samer Chmait, Xiaoning Zhao, Carl D. Davis, Silke Miller, Geraldine Hill Della Puppa, Mary Dovlatyan, Hang Chen, Dianna Lester-Zeiner, Jessica Able, Christopher Biorn, Ji Ma, Jianxia Shi, James Treanor, Jennifer R. Allen   +15 more
openalex   +1 more source

Structural insight into the lead identification of a dual inhibitor of PDE1B and PDE10A: Integrating pharmacophore-based virtual screening, molecular docking, and structure-activity-relationship approaches. [PDF]

Heliyon
Soon CW, Gaurav A, Gautam V, Al-Nema M.
europepmc   +1 more source

Evaluating the antipsychotic profile of the preferential PDE10A inhibitor, papaverine

, 2008
Martin Weber, Michelle R. Breier, D. Ko, Niveditha Thangaraj, David Marzan, Neal R. Swerdlow   +5 more
openalex   +1 more source