Robust protein-ligand interaction modeling through integrating physical laws and geometric knowledge for absolute binding free energy calculation. [PDF]
Chem SciSu Q +11 more
europepmc +1 more source
Synthesis of Tryptamine-Thiazolidin-4-one Derivatives and the Combined In Silico and In Vitro Evaluation of their Biological Activity and Cytotoxicity. [PDF]
ACS OmegaAydın S +6 more
europepmc +1 more source
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype. [PDF]
Genes DevNuechterlein N +27 more
europepmc +1 more source
Carbon-11 labeled papaverine as a PET tracer for imaging PDE10A: radiosynthesis, in vitro and in vivo evaluation [PDF]
, 2010 Zhude Tu +4 more
openalex +1 more source
Potent and sustained enhancement of human sperm motility using novel cyclic AMP upregulators. [PDF]
ReproductionOscoz-Susino N +8 more
europepmc +1 more source
Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A) [PDF]
, 2014 Essa Hu +15 more
openalex +1 more source
A phase 1 study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of TAK-063, a selective PDE10A inhibitor [PDF]
, 2016 Max Tsai +4 more
openalex +1 more source
Identification of Novel Quinolone and Quinazoline Alkaloids as Phosphodiesterase 10A Inhibitors for Parkinson's Disease through a Computational Approach. [PDF]
ACS OmegaAhmad I +11 more
europepmc +1 more source
Highlights lecture EANM 2014: “Gimme gimme gimme those nuclear Super Troupers” [PDF]
, 2015 core +1 more source
Potential of PDE10A Inhibitors as Treatment for Schizophrenia and Other Neurological Disorders [PDF]
ACS Medicinal Chemistry Letters, 2018 openaire +2 more sources