Phloroglucinol inhibits human ureteral contractions via activation of cAMP‐PKA pathway
Abstract Background and Purpose Phloroglucinol is used to treat renal colic, especially when non‐steroidal anti‐inflammatory drugs are contraindicated. This study aimed to clarify its mechanism by examining effects on human ureteral contractility and underlying signalling pathways. Experimental Approach Urinary levels of neurokinin A (NKA), substance P
Hanwen Liu +12 more
wiley +1 more source
Learning variable-order time fractional diffusion equations using Physics-Informed Neural Networks. [PDF]
Ren L, Jin S.
europepmc +1 more source
Adenosine A2A receptor (ADORA2A); phosphodiesterase-2 (PDE-2); PDE-3; PDE-4; PDE-7 [PDF]
openaire +1 more source
Computing Skinning Weights via Convex Duality
We present an alternate optimization method to compute bounded biharmonic skinning weights. Our method relies on a dual formulation, which can be optimized with a nonnegative linear least squares setup. Abstract We study the problem of optimising for skinning weights through the lens of convex duality.
J. Solomon, O. Stein
wiley +1 more source
A fission yeast-based platform for nematode PDE inhibitor discovery. [PDF]
Bibeau S +17 more
europepmc +1 more source
SDFs from Unoriented Point Clouds using Neural Variational Heat Distances
We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from unoriented point clouds. We first compute a small time step of heat flow (middle) and then use its gradient directions to solve for a neural SDF (right). Abstract We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from ...
Samuel Weidemaier +5 more
wiley +1 more source
Peritoneal exosomes mediate activation of CD4<sup>+</sup> T cells and enhancement of vaccine efficacy in teleost. [PDF]
Shi X +10 more
europepmc +1 more source
Controllable Intrinsic Surface Pattern Generation Using Slime Mold Simulations
Abstract Surface‐based pattern simulations have proven valuable for texture design and scientific visualization, but existing methods face several limitations. Most simulations either target a narrow range of pattern types (e.g. spots, branching) or support a broad range of patterns at the cost of time‐consuming parameter tuning.
Jeffrey Layton +2 more
wiley +1 more source
Volumetric Ablation of Phenolic Resin in Extreme Environments: A Variable-Property Physics-Informed Neural Network Framework. [PDF]
Du W, Ma T, Song H.
europepmc +1 more source
Mesh Processing Non‐Meshes via Neural Displacement Fields
Abstract Mesh processing pipelines are mature, but adapting them to newer non‐mesh surface representations—which enable fast rendering with compact file size—requires costly meshing or transmitting bulky meshes, negating their core benefits for streaming applications.
Yuta Noma +4 more
wiley +1 more source

