Results 121 to 130 of about 217,226 (371)

Plant‐derived exosomes: A Green Nanomedicine for Cancer

open access: yesClinical and Translational Discovery
Exosomes are signalling molecules related to cell‐to‐cell communication. Based on sources (plants, stem cells, and immune cells derived exosomes) it offers promising therapeutic activity against cancer.
Swarup Sonar, Krishnan Anand
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Local Polynomial Regression and Filtering for a Versatile Mesh‐Free PDE Solver

open access: yesInternational Journal for Numerical Methods in Fluids, EarlyView.
A high‐order, mesh‐free finite difference method for solving differential equations is presented. Both derivative approximation and scheme stabilisation is carried out by parametric or non‐parametric local polynomial regression, making the resulting numerical method accurate, simple and versatile. Numerous numerical benchmark tests are investigated for
Alberto M. Gambaruto
wiley   +1 more source

The homogeneous balance of undetermined coefficients method and its application

open access: yesOpen Mathematics, 2016
The homogeneous balance of undetermined coefficients method is firstly proposed to solve such nonlinear partial differential equations (PDEs), the balance numbers of which are not positive integers.
Wei Yi, He Xin-Dang, Yang Xiao-Feng
doaj   +1 more source

Strong-viscosity Solutions: Semilinear Parabolic PDEs and Path-dependent PDEs

open access: yes, 2019
The aim of the present work is the introduction of a viscosity type solution, called strong-viscosity solution to distinguish it from the classical one, with the following peculiarities: it is a purely analytic object; it can be easily adapted to more ...
Cosso, Andrea, Russo, Francesco
core  

Fast Calculation for the Flow and Heat Transfer of Tempered Fractional Maxwell Viscoelastic Fluid

open access: yesInternational Journal for Numerical Methods in Fluids, EarlyView.
This study develops a tempered fractional Maxwell model to simulate unsteady thermal flow in viscoelastic fluids, capturing key rheological behaviors. A fast SOE‐based algorithm is proposed to improve the computational efficiency of the numerical scheme. Results reveal how key parameters influence fluid motion and heat transfer, demonstrating the model'
Yi Liu, Mochen Jiang, Libo Feng
wiley   +1 more source

Intraoperative Molecular Imaging Can Detect Large Nerve Perineural Invasion: A Case Report

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Perineural invasion (PNI) in head and neck squamous cell carcinoma (SCC) results in worse overall survival. Diagnosis requires resection and microscopic evaluation. Methods A 63‐year‐old male with persistent cT4aN0 p16‐positive SCC of the left base of tongue following chemoradiotherapy underwent salvage total glossectomy ...
Carleigh R. Burns   +9 more
wiley   +1 more source

New Drain Spacing Formulas Using the Variational Iteration Method

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT In this study, the drain spacing is computed using the variational iteration method (VIM) to the linearized Boussinesq equation. By applying at most two iterations of the VIM method under three different initial condition scenarios, three equations for drain spacing calculation were derived. These equations predict values of drain spacing that
George Kargas   +2 more
wiley   +1 more source

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